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Research Article| Volume 64, ISSUE 1, P55-64, April 1984

Multiple innervation of human muscle fibers

  • Alan J. McComas
    Affiliations
    Department of Medicine, McMaster University Medical Centre, P. O. Box 2000, Hamilton, Ont. L8N 3Z5 Canada

    Department of Neurosciences, McMaster University Medical Centre, P. O. Box 2000, Hamilton, Ont. L8N 3Z5 Canada
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  • Stjepan Kereshi
    Affiliations
    Department of Medicine, McMaster University Medical Centre, P. O. Box 2000, Hamilton, Ont. L8N 3Z5 Canada

    Department of Neurosciences, McMaster University Medical Centre, P. O. Box 2000, Hamilton, Ont. L8N 3Z5 Canada
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  • Gilberto Manzano
    Affiliations
    Department of Medicine, McMaster University Medical Centre, P. O. Box 2000, Hamilton, Ont. L8N 3Z5 Canada

    Department of Neurosciences, McMaster University Medical Centre, P. O. Box 2000, Hamilton, Ont. L8N 3Z5 Canada
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      Abstract

      A combination of electrophysiological techniques, including stimulus threshold measurements, coaxial needle recordings of voluntary EMG, and evoked response analysis, has been used to show that the motor innervation of the human biceps brachii has an extensive distribution in the long axis of the muscle. Impulse collision experiments, involving either excitation at two sites or the use of stimuli of graded intensity, have demonstrated that the diffuse muscle innervation is partly a consequence of individual muscle fibers having more than one end-plate

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