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Research Article| Volume 54, ISSUE 2, P197-208, May 1982

Changes in peripheral nerve fibres distal to a constriction

DOI:https://doi.org/10.1016/0022-510X(82)90182-4
Changes in peripheral nerve fibres distal to a constriction
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      Abstract

      Continued constriction of the tibial nerve of the rabbit by a ligature was accompanied by a reduction in maximal motor conduction velocity distal to the ligature, and by a reduction in axonal and total fibre diameter. From the presence of paranodal demyelination and distal fibre degeneration in severely affected nerves, it is suggested that in some instances the change in axonal calibre was part of a progressive distal atrophy which could lead to secondary demyelination and ultimately to “dying-back” of the affected axons.
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      Article info

      Publication history

      Accepted: October 29, 1981
      Received: September 21, 1981

      Footnotes

      ☆This study was supported financially by the Medical Research Council, the Wellcome Trust and the Brain Research Trust.

      ☆Based on a paper presented to the Peripheral Nerve Study Group in Shakertown, Kentucky, July 1981.

      Identification

      DOI: https://doi.org/10.1016/0022-510X(82)90182-4

      Copyright

      © 1982 Published by Elsevier Inc.

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