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Research Article| Volume 47, ISSUE 1, P79-91, July 1980

Cytochrome c oxidase activity and fatty acid oxidation in various types of human muscle

DOI:https://doi.org/10.1016/0022-510X(80)90027-1
Cytochrome c oxidase activity and fatty acid oxidation in various types of human muscle
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      Abstract

      Cytochrome c oxidase activity, carnitine concentration and oxidation rates of pyruvate and palmitate were determined in homogenates of various types of human skeletal muscle. Cytochrome c oxidase activity appeared to be closely related to the pyruvate oxidation rate, but its correlation with palmitate oxidation was less distinct.
      Trunk muscles oxidize less palmitate and have a lower cytochrome c oxidase activity per mg homogenate protein than leg muscles; soleus muscle biopsies showed higher activities than those of other leg muscles. Based on cytochrome c oxidase activity no large differences are found in palmitate oxidation rate between various types of human muscle.
      Cytochrome c oxidase activity and palmitate oxidation rate of muscles do not show an age dependency.
      The carnitine concentration is similar in all kinds of human skeletal muscle.
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      Article info

      Publication history

      Accepted: March 13, 1980
      Received in revised form: March 10, 1980
      Received: December 17, 1979

      Footnotes

      ☆This work was supported by the Prinses Beatrix Fonds.

      Identification

      DOI: https://doi.org/10.1016/0022-510X(80)90027-1

      Copyright

      © 1980 Published by Elsevier Inc.

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