Research Article| Volume 18, ISSUE 1, P89-110, January 1973

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A surgical investigation of the clinical physiology of the LP-pulvinar complex in man

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      Cryogenic stereotactic lesions were placed in 55 pulvinar and 9 lateralis-posterior (LP) nuclei of 49 patients suffering from dystonia, athetosis, spasticity, torticollis, intractable pain, and other miscellaneous conditions. Ten of 19 cases (52.5%) of dystonia, 10 of 16 cases (62.5%) of athetosis and 7 of 10 cases (70%) of spasticity improved significantly following the cryogenic lesion. Thirteen patients with primary or secondary intractable pain were pain-free following surgery. No deleterious effects on motor, sensory, behavioral, or speech and language functions were noted. Electrophysiological studies during surgery not only helped in localisation of the pulvinar and LP nuclei but a wide distribution of evoked potentials from cortex was recorded following their stimulation. It appears that the pulvinar of man contributes to motor function. The LP-pulvinar complex is a poly-sensory data processor, contributing to a wide range of somato-sensory functions.
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