Journal of the Neurological Sciences
Volume 298, Issue 1 , Pages 11-16, 15 November 2010

The pre-requisite of a second-generation glioma PET biomarker

  • Katalin Borbely

      Affiliations

    • PET/CT Amb, National Institute of Oncology, 1122 Budapest, Rath Gyorgy 7-9, Hungary
    • Corresponding Author InformationCorresponding author. Tel.: +36 1 224 8600; fax: +36 1 224 8720.
    • ,
  • Max Wintermark

      Affiliations

    • Neuroradiology Division, University of Virginia, Department of Radiology, Charlottesville, VA, USA
    • Tel.: +1 434 243 9312; fax: +1 434 982 5753.
    • ,
  • Janos Martos

      Affiliations

    • Department of Neuroradiology, National Institute of Neurosurgery, 1145 Budapest, Amerikai 45, Hungary
    • Tel.: +36 1 2512999; fax: +36 1 2515678.
    • ,
  • Imre Fedorcsak

      Affiliations

    • Department of Neurosurgery, National Institute of Neurosurgery, 1145 Budapest, Amerikai 45, Hungary
    • Tel.: +36 1 2512999; fax: +36 1 2515678.
    • ,
  • Laszlo Bognar

      Affiliations

    • Department of Neurosurgery, Debrecen University Medical Faculties, 4032 Debrecen, Nagyerdei krt 98, Hungary
    • Tel.: +36 52 411 717; fax: +36 52 419 418.
    • ,
  • Miklos Kasler

      Affiliations

    • National Institute of Oncology, 1122 Budapest, Rath Gyorgy 7-9, Hungary
    • Tel.: +36 1 224 8600; fax: +36 1 8667.

Received 2 June 2010; received in revised form 23 July 2010; accepted 27 July 2010. published online 26 August 2010.

Abstract 

Since the introduction of FDG into the field of molecular imaging with positron emission tomography (PET) more than three decades ago, FDG has been the tracer of choice for oncology PET imaging. Despite the relative disadvantages of FDG and the relative benefits of its challengers, FDG remains the most commonly used glioma tracer nowadays. The present article surveys the expectations of the field and gives a concise summary of recent developments; including the issues pertaining to the continued search for an optimal second-generation PET biomarker for glioma.

Mini-abstract

The present article gives a concise summary of recent developments; including the issues pertaining to the continued search for an optimal PET biomarker for glioma.

Keywords: Glioma, PET, Biomarker

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PII: S0022-510X(10)00347-3

doi:10.1016/j.jns.2010.07.024

Journal of the Neurological Sciences
Volume 298, Issue 1 , Pages 11-16, 15 November 2010

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