Journal of the Neurological Sciences
Volume 299, Issue 1 , Pages 120-125 , 15 December 2010

Cerebro- and cardiovascular reactivity and neuropsychological performance in hypertensive patients

  • Katalin Réka Kovács

      Affiliations

    • Department of Neurology, University of Debrecen Medical and Health Science Center, Debrecen, Hungary
  • ,
  • Csilla Cecília Szekeres

      Affiliations

    • Department of Neurology, Mureş County Clinical Emergency Hospital, Târgu-Mureş, Romania
  • ,
  • Zoltán Bajkó

      Affiliations

    • Department of Neurology, Mureş County Clinical Emergency Hospital, Târgu-Mureş, Romania
  • ,
  • Krisztina Csapó

      Affiliations

    • Department of Neurology, University of Debrecen Medical and Health Science Center, Debrecen, Hungary
  • ,
  • Sándor Molnár

      Affiliations

    • Department of Neurology, University of Debrecen Medical and Health Science Center, Debrecen, Hungary
  • ,
  • László Oláh

      Affiliations

    • Department of Neurology, University of Debrecen Medical and Health Science Center, Debrecen, Hungary
  • ,
  • Mária Tünde Magyar

      Affiliations

    • Department of Neurology, University of Debrecen Medical and Health Science Center, Debrecen, Hungary
  • ,
  • Dániel Bereczki

      Affiliations

    • Department of Neurology, Semmelweis University, Budapest, Hungary
  • ,
  • László Kardos

      Affiliations

    • Contract Medical Statistician, Kenézy Gyula Hospital, Debrecen, Hungary
  • ,
  • Pál Soltész

      Affiliations

    • 3rd Department of Internal Medicine, University of Debrecen Medical and Health Science Center, Debrecen, Hungary
  • ,
  • Andrea Burainé Bojtor

      Affiliations

    • Department of Neurology, University of Debrecen Medical and Health Science Center, Debrecen, Hungary
  • ,
  • László Csiba

      Affiliations

    • Department of Neurology, University of Debrecen Medical and Health Science Center, Debrecen, Hungary
    • Corresponding Author InformationCorresponding author. Department of Neurology, University of Debrecen Medical and Health Science Center, Móricz Zsigmond str. 22, 4032 Debrecen, Hungary. Tel.: +36 52 255 255; fax: +36 52 453 590.

Received 30 April 2010 ,Accepted 24 July 2010.

References 

  1. Cheng KS, Baker CR, Hamilton G, Hoeks AP, Seifalian AM. Arterial elastic properties and cardiovascular risk/event. Eur J Vasc Endovasc Surg. 2002;24:383–397
  2. Knecht S, Wersching H, Lohmann H, Berger K, Ringelstein EB. How much does hypertension affect cognition?: explained variance in cross-sectional analysis of non-demented community-dwelling individuals in the SEARCH study. J Neurol Sci. 2009;283:149–152
  3. Saini M, Shuaib A. Blood pressure lowering and stroke. Expert Rev Neurother. 2010;10:225–241
  4. Kilander L, Nyman H, Boberg M, Hansson L, Lithell H. Hypertension is related to cognitive impairment: a 20-year follow-up of 999 men. Hypertension. 1998;31:780–786
  5. Sepe-Monti M, Pantano P, Vanacore N, et al. Vascular risk factors and white matter hyperintensities in patients with amnestic mild cognitive impairment. Acta Neurol Scand. 2007;115:419–424
  6. Elias PK, Elias MF, Robbins MA, Budge MM. Blood pressure-related cognitive decline: does age make a difference?. Hypertension. 2004;44:631–636
  7. Brady CB, Spiro A, Gaziano JM. Effects of age and hypertension status on cognition: the veterans affairs normative aging study. Neuropsychology. 2005;19:770–777
  8. Jonas BS, Franks P, Ingram DD. Are symptoms of anxiety and depression risk factors for hypertension? Longitudinal evidence from the National Health and Nutrition Examination Survey I epidemiologic follow-up study. Arch Fam Med. 1997;6:43–49
  9. Abramson J, Berger A, Krumholz HM, Vaccarino V. Depression and risk of heart failure among older persons with isolated systolic hypertension. Arch Intern Med. 2001;161:1725–1730
  10. Tan MP, Duncan GW, Parry SW. Head-up Tilt Table Testing: a state-of-the-art review. Minerva Med. 2009;100:329–338
  11. Eguchi K, Kario K, Hoshide S, Hoshide Y, Ishikawa J, Morinari M, et al. Greater change of orthostatic blood pressure is related to silent cerebral infarct and cardiac overload in hypertensive subjects. Hypertens Res. 2004;27:235–241
  12. Makowski K, Gielerak G, Cholewa M, Kramarz E, Michalkiewicz D, Kaminski G, et al. Autonomic nervous system and left ventricular hypertrophy in essential hypertension. Kardiol Pol. 2002;57:520–531discussion 532
  13. Kario K, Eguchi K, Hoshide S, Hoshide Y, Umeda Y, Mitsuhashi T, et al. U-curve relationship between orthostatic blood pressure change and silent cerebrovascular disease in elderly hypertensives: orthostatic hypertension as a new cardiovascular risk factor. J Am Coll Cardiol. 2002;40:133–141
  14. European Society of Hypertension-European Society of Cardiology Guidelines Committee . European Society of Hypertension-European Society of Cardiology guidelines for the management of arterial hypertension. J Hypertens. 2003;21:1011–1053
  15. Naschitz JE, Fefer F, Boyer S, Mazov I, Sabo E, Yeshurun D, et al. Comparison of the 10minute supine—30minute tilt test with 24h ambulatory blood pressure for the diagnosis of diastolis systemic hypertension. Am J Cardiol. 1995;76:366–369
  16. Naschitz JE, Sabo E, Gaitini L, Ahdoot A, Ahdoot M, Shaviv N, et al. The Haemodynamic Instability Score (HIS) for assessment of cardiovascular reactivity in hypertensive and normotensive patients. J Hum Hypertens. 2001;15:177–184
  17. Matthews KA, Woodall KL, Allen MT. Cardiovascular reactivity to stress predicts future blood pressure status. Hypertension. 1993;22:479–585
  18. Strandgaard S, Paulson OB. Cerebral blood flow in untreated and treated hypertension. Neth J Med. 1995;47:180–184
  19. Blumenthal JA, Madden DJ, Pierce TW, Siegel WC, Appelbaum M. Hypertension affects neurobehavioral functioning. Psychosom Med. 1993;55:44–50
  20. Waldstein SR, Katzel LI. Hypertension and cognitive function. In:  Waldstein SR,  Elias MF editor. Neuropsychology of Cardiovascular Disease. Mahwah, NJ: Lawrence Erlbaum Associates; 2001;p. 15–36
  21. Vetere G, Ripaldi L, Ais E, Korob G, Kes M, Villamil A. Prevalence of anxiety disorders in patients with essential hypertension. Vertex. 2007;18:20–25

PII: S0022-510X(10)00345-X

doi: 10.1016/j.jns.2010.07.022

Journal of the Neurological Sciences
Volume 299, Issue 1 , Pages 120-125 , 15 December 2010