Journal of the Neurological Sciences
Volume 292, Issue 1 , Pages 40-44 , 15 May 2010

Kallmann syndrome and mirror movements: White matter quantitative evaluation with magnetic resonance imaging

  • Marcel Koenigkam-Santos

      Affiliations

    • Division of Radiology, School of Medicine of Ribeirao Preto, University of Sao Paulo; Ribeirao Preto, SP, Brazil
    • Corresponding Author InformationCorresponding author. Department of Radiology School of Medicine of Ribeirao Preto, University of Sao Paulo, Av. Bandeirantes, 3900, Campus Universitario, Monte Alegre 14048-900, Ribeirao Preto, Sao Paulo, Brazil. Tel.: +55 16 36022640/36372712; fax: +55 16 36022648.
  • ,
  • Margaret de Castro

      Affiliations

    • Division of Endocrinology & Metabolism, Department of Internal Medicine, School of Medicine of Ribeirao Preto, University of Sao Paulo; Ribeirao Preto, SP, Brazil
  • ,
  • Beatriz R. Versiani

      Affiliations

    • Division of Endocrinology & Metabolism, Department of Internal Medicine, School of Medicine of Ribeirao Preto, University of Sao Paulo; Ribeirao Preto, SP, Brazil
  • ,
  • Paula Rejane B. Diniz

      Affiliations

    • Division of Radiology, School of Medicine of Ribeirao Preto, University of Sao Paulo; Ribeirao Preto, SP, Brazil
  • ,
  • Antonio Carlos Santos

      Affiliations

    • Division of Radiology, School of Medicine of Ribeirao Preto, University of Sao Paulo; Ribeirao Preto, SP, Brazil

Received 27 September 2009 ,Revised 9 February 2010 ,Accepted 11 February 2010.

References 

  1. Seminara SB, Hayes FJ, Crowley WF. Gonadotropin-releasing hormone deficiency in the human (idiopathic hypogonadotropic hypogonadism and Kallmann's syndrome): pathophysiological and genetic considerations. Endocr Rev. 1998;19:521–539
  2. Quinton R, Duke VM, Robertson A, Kirk JM, Matfin G, de Zoysa PA, et al. Idiopathic gonadotrophin deficiency: genetic questions addressed through phenotypic characterization. Clin Endocrinol (Oxf). 2001;55:163–174
  3. Sato N, Katsumata N, Kagami M, Hasegawa T, Hori N, Kawakita S, et al. Clinical assessment and mutation analysis of Kallmann syndrome 1 (KAL1) and fibroblast growth factor receptor 1 (FGFR1, or KAL2) in five families and 18 sporadic patients. J Clin Endocrinol Metab. 2004;89:1079–1088
  4. Mayston MJ, Harrison LM, Stephens JA. A neurophysiological study of mirror movements in adults and children. Ann Neurol. 1999;45:583–594
  5. Krams M, Quinton R, Mayston MJ, Harrison LM, Dolan RJ, Bouloux PM, et al. Mirror movements in X-linked Kallmann's syndrome. II. A PET study. Brain. 1997;120:1217–1228
  6. Leinsinger GL, Heiss DT, Jassoy AG, Pfluger T, Hahn K, Danek A. Persistent mirror movements: functional MR imaging of the hand motor cortex. Radiology. 1997;203:545–552
  7. Mayer M, Schulze S, Danek A, Botzel K. Dipole source analysis in persistent mirror movements. Brain Topogr. 1999;12:49–60
  8. Koenigkam-Santos M, Santos AC, Borduqui T, Versiani BR, Hallak JE, Crippa JA, et al. Whole-brain voxel-based morphometry in Kallmann syndrome associated with mirror movements. AJNR Am J Neuroradiol. 2008;29:1799–1804
  9. Quinton R, Duke VM, de Zoysa PA, Platts AD, Kendall B, et al. The neuroradiology of Kallmann's syndrome: a genotypic and phenotypic analysis. J Clin Endocrinol Metab. 1996;81:3010–3017
  10. Krams M, Quinton R, Ashburner J, Friston KJ, Frackowiak RS, Bouloux PM, et al. Kallmann's syndrome: mirror movements associated with bilateral corticospinal tract hypertrophy. Neurology. 1999;52:816–822
  11. Mamere AE, Saraiva LA, Matos AL, Carneiro AA, Santos AC. Evaluation of delayed neuronal and axonal damage secondary to moderate and severe traumatic brain injury using quantitative MR imaging techniques. AJNR Am J Neuroradiol. 2009;30:947–952
  12. Versiani BR, Trarbach E, Koenigkam-Santos M, Dos Santos AC, Elias LL, Moreira AC, et al. Clinical assessment and molecular analysis of GnRHR and KAL1 genes in males with idiopathic hypogonadotrophic hypogonadism. Clin Endocrinol (Oxf). 2007;66:173–179
  13. Barnes D, McDonald WI, Landon DN, Johnson G. The characterization of experimental gliosis by quantitative nuclear magnetic resonance imaging. Brain. 1988;111:83–94
  14. Larsson HB, Frederiksen J, Petersen J, Nordenbo A, Zeeberg I, Henriksen O, et al. Assessment of demyelination, edema, and gliosis by in vivo determination of T1 and T2 in the brain of patients with acute attack of multiple sclerosis. Magn Reson Med. 1989;11:337–348
  15. Kaltwasser JP, Gottschalk R, Schalk KP, Hartl W. Non-invasive quantitation of liver iron-overload by magnetic resonance imaging. Br J Haematol. 1990;74:360–363
  16. Bernasconi A, Bernasconi N, Caramanos Z, Reutens DC, Andermann F, Dubeau F, et al. T2 relaxometry can lateralize mesial temporal lobe epilepsy in patients with normal MRI. NeuroImage. 2000;12:739–746
  17. Papanikolaou N, Papadaki E, Karampekios S, Spilioti M, Maris T, Prassopoulos P, et al. T2 relaxation time analysis in patients with multiple sclerosis: correlation with magnetization transfer ratio. Eur Radiol. 2004;14:115–122
  18. Wolff SD, Balaban RS. Magnetization transfer contrast (MTC) and tissue water proton relaxation in vivo. Magn Reson Med. 1989;10:135–144
  19. Kimura H, Grossman RI, Lenkinski RE, Gonzalez-Scarano F. Proton MR spectroscopy and magnetization transfer ratio in multiple sclerosis: correlative findings of active versus irreversible plaque disease. AJNR Am J Neuroradiol. 1996;17:1539–1547
  20. Henkelman RM, Stanisz GJ, Graham SJ. Magnetization transfer in MRI: a review. NMR in biomedicine. 2001;14:57–64
  21. Dousset V, Grossman RI, Ramer KN, Schnall MD, Young LH, Gonzalez-Scarano F, et al. Experimental allergic encephalomyelitis and multiple sclerosis: lesion characterization with magnetization transfer imaging. Radiology. 1992;182:483–491
  22. Filippi M, Rocca MA, Martino G, Horsfield MA, Comi G. Magnetization transfer changes in the normal appearing white matter precede the appearance of enhancing lesions in patients with multiple sclerosis. Ann Neurol. 1998;43:809–814
  23. Bagley LJ, Grossman RI, Galetta SL, Sinson GP, Kotapka M, McGowan JC. Characterization of white matter lesions in multiple sclerosis and traumatic brain injury as revealed by magnetization transfer contour plots. AJNR Am J Neuroradiol. 1999;20:977–981
  24. Berry I, Barker GJ, Barkhof F, Campi A, Dousset V, Franconi JM, et al. A multicenter measurement of magnetization transfer ratio in normal white matter. J Magn Reson Imaging. 1999;9:441–446
  25. McGowan JC. The physical basis of magnetization transfer imaging. Neurology. 1999;53:S3–S7
  26. Sinson G, Bagley LJ, Cecil KM, Torchia M, McGowan JC, Lenkinski RE, et al. Magnetization transfer imaging and proton MR spectroscopy in the evaluation of axonal injury: correlation with clinical outcome after traumatic brain injury. AJNR Am J Neuroradiol. 2001;22:143–151
  27. Nass R. Mirror movement asymmetries in congenital hemiparesis: the inhibition hypothesis revisited. Neurology. 1985;35(7):1059–1062
  28. Mukherjee P, McKinstry RC. Diffusion tensor imaging and tractography of human brain development. Neuroimaging Clin N Am. 2006;16:19–43
  29. Trarbach EB, Costa EM, Versiani B, de Castro M, Baptista MT, Garmes HM, et al. Novel fibroblast growth factor receptor 1 mutations in patients with congenital hypogonadotropic hypogonadism with and without anosmia. J Clin Endocrinol Metab. 2006;91:4006–4012

PII: S0022-510X(10)00086-9

doi: 10.1016/j.jns.2010.02.010

Journal of the Neurological Sciences
Volume 292, Issue 1 , Pages 40-44 , 15 May 2010