Journal of the Neurological Sciences
Volume 291, Issue 1 , Pages 37-43 , 15 April 2010

Reappraisal of brain MRI features in patients with multiple sclerosis and neuromyelitis optica according to anti-aquaporin-4 antibody status

  • Takuya Matsushita

      Affiliations

    • Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    • ,
  • Noriko Isobe

      Affiliations

    • Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    • ,
  • Hua Piao

      Affiliations

    • Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    • ,
  • Takeshi Matsuoka

      Affiliations

    • Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    • ,
  • Takaaki Ishizu

      Affiliations

    • Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    • ,
  • Hikaru Doi

      Affiliations

    • Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    • ,
  • Katsuhisa Masaki

      Affiliations

    • Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    • ,
  • Takashi Yoshiura

      Affiliations

    • Division of Neuroradiology, Department of Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    • ,
  • Ryo Yamasaki

      Affiliations

    • Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    • ,
  • Yasumasa Ohyagi

      Affiliations

    • Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    • ,
  • Jun-ichi Kira

      Affiliations

    • Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    • Corresponding Author InformationCorresponding author. Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University, 311 Maidashi, Higashi-ku, Fukuoka 8128582, Japan. Tel.: +81 926425340; fax: +81 926425352.

Received 16 February 2009 ,Revised 15 December 2009 ,Accepted 11 January 2010.

References 

  1. de Seze J. Neuromyelitis optica. Arch Neurol. 2003;60:1336–1338
  2. Wingerchuk DM, Hogancamp WF, O'Brien PC, Weinshenker BG. The clinical course of neuromyelitis optica (Devic's syndrome). Neurology. 1999;53:1107–1114
  3. Wingerchuk DM, Lennon VA, Pittock SJ, Lucchinetti CF, Weinshenker BG. Revised diagnostic criteria for neuromyelitis optica. Neurology. 2006;66:1485–1489
  4. Lennon VA, Wingerchuk DM, Kryzer TJ, Pittock SJ, Lucchinetti CF, Fujihara K, et al. A serum autoantibody marker of neuromyelitis optica: distinction from multiple sclerosis. Lancet. 2004;364:2106–2112
  5. Lennon VA, Kryzer TJ, Pittock SJ, Verkman AS, Hinson SR. IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water channel. J Exp Med. 2005;202:473–477
  6. Pittock SJ, Lennon VA, Krecke K, Wingerchuk DM, Lucchinetti CF, Weinshenker BG. Brain MRI abnormalities in neuromyelitis optica. Arch Neurol. 2006;63:390–396
  7. Lucchinetti CF, Mandler RN, McGavern D, Bruck W, Gleich G, Ransohoff RM, et al. A role for humoral mechanisms in the pathogenesis of Devic's neuromyelitis optica. Brain. 2002;125:1450–1461
  8. Roemer SF, Parisi JE, Lennon VA, Benarroch EE, Lassmann H, Bruck W, et al. Pattern-specific loss of aquaporin-4 immunoreactivity distinguishes neuromyelitis optica from multiple sclerosis. Brain. 2007;130:1194–1205
  9. Misu T, Fujihara K, Kakita A, Konno H, Nakamura M, Watanabe S, et al. Loss of aquaporin-4 in lesions of neuromyelitis optica: distinction from multiple sclerosis. Brain. 2007;130:1224–1234
  10. Nakashima I, Fujihara K, Miyazawa I, Misu T, Narikawa K, Nakamura M, et al. Clinical and MRI features of Japanese patients with multiple sclerosis positive for NMO-IgG. J Neurol Neurosurg Psychiatry. 2006;77:1073–1075
  11. Matsuoka T, Matsushita T, Kawano Y, Osoegawa M, Ochi H, Ishizu T, et al. Heterogeneity of aquaporin-4 autoimmunity and spinal cord lesions in multiple sclerosis in Japanese. Brain. 2007;130:1206–1223
  12. Poser CM, Paty DW, Scheinberg L, McDonald WI, Davis FA, Ebers GC, et al. New diagnostic criteria for multiple sclerosis: guidelines for research protocols. Ann Neurol. 1983;13:227–231
  13. Paty DW, Oger JJ, Kastrukoff LF, Hashimoto SA, Hooge JP, Eisen AA, et al. MRI in the diagnosis of MS: a prospective study with comparison of clinical evaluation, evoked potentials, oligoclonal banding, and CT. Neurology. 1988;38:180–185
  14. Polman CH, Reingold SC, Edan G, Filippi M, Hartung HP, Kappos L, et al. Diagnostic criteria for multiple sclerosis: 2005 revisions to the “McDonald Criteria”. Ann Neurol. 2005;58:840–846
  15. Su JJ, Osoegawa M, Minohara M, Tanaka M, Ishizu T, Mihara F, et al. Upregulation of vascular growth factors in multiple sclerosis: correlation with MRI findings. J Neurol Sci. 2006;243:21–30
  16. Barkhof F, Filippi M, Miller DH, Scheltens P, Campi A, Polman CH, et al. Comparison of MRI criteria at first presentation to predict conversion to clinically definite multiple sclerosis. Brain. 1997;120:2059–2069
  17. Kurtzke JF. Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS). Neurology. 1983;33:1444–1452
  18. Fog T. The topography of plaques in multiple sclerosis with special reference to cerebral plaques. Acta Neurol Scand. 1965;15:1–161
  19. Mathey EK, Derfuss T, Storch MK, Williams KR, Hales K, Woolley DR, et al. Neurofascin as a novel target for autoantibody-mediated axonal injury. J Exp Med. 2007;204:2363–2372
  20. Matsushita T, Isobe N, Matsuoka T, Ishizu T, Kawano Y, Yoshiura T, et al. Extensive vasogenic edema of anti-aquaporin-4 antibody-related brain lesions. Mult Scler. 2009;15:1113–1117
  21. Manley GT, Fujimura M, Ma T, Noshita N, Filiz F, Bollen AW, et al. Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke. Nat Med. 2000;6:159–163
  22. Papadopoulos MC, Manley GT, Krishna S, Verkman AS. Aquaporin-4 facilitates reabsorption of excess fluid in vasogenic brain edema. FASEB J. 2004;18:1291–1293
  23. Compston A, Coles A. Multiple sclerosis. Lancet. 2002;359:1221–1231
  24. Kira J, Kanai T, Nishimura Y, Yamasaki K, Matsushita S, Kawano Y, et al. Western versus Asian types of multiple sclerosis: immunogenetically and clinically distinct disorders. Ann Neurol. 1996;40:569–574
  25. Nakashima I, Fujihara K, Itoyama Y. Oligoclonal IgG bands in Japanese multiple sclerosis patients. J Neuroimmunol. 1999;101:205–206
  26. Li B, Dong H, Zhang J, Song X, Guo L. Cerebrospinal fluid IgG profiles and oligoclonal bands in Chinese patients with multiple sclerosis. Acta Neurol Scand. 2007;115:319–324

PII: S0022-510X(10)00017-1

doi: 10.1016/j.jns.2010.01.009

Journal of the Neurological Sciences
Volume 291, Issue 1 , Pages 37-43 , 15 April 2010

Article Tools

* Image Usage & Resolution