Journal of the Neurological Sciences
Volume 290, Issue 1 , Pages 190-193 , 15 March 2010

Wedge-shaped medullary lesions in multiple sclerosis

  • Wei Qiu

      Affiliations

    • Centre for Neuromuscular and Neurological disorders, University of Western Australia, Australia
    • Department of Neurology, Sir Charles Gairdner Hospital, Queen Elizabeth II Medical Centre, Perth, Western Australia, Australia
    • Department of Neurology, the Third Affiliated Hospital of Sun yat-sen University, Guangzhou, China
  • ,
  • Sonja Raven

      Affiliations

    • Neurointerventional and Imaging Services of Western Australia, Perth, Western Australia, Australia
  • ,
  • Jing-Shan Wu

      Affiliations

    • Centre for Neuromuscular and Neurological disorders, University of Western Australia, Australia
    • Department of Neurology, Sir Charles Gairdner Hospital, Queen Elizabeth II Medical Centre, Perth, Western Australia, Australia
  • ,
  • William M. Carroll

      Affiliations

    • Centre for Neuromuscular and Neurological disorders, University of Western Australia, Australia
    • Department of Neurology, Sir Charles Gairdner Hospital, Queen Elizabeth II Medical Centre, Perth, Western Australia, Australia
  • ,
  • Frank L. Mastaglia

      Affiliations

    • Centre for Neuromuscular and Neurological disorders, University of Western Australia, Australia
    • Department of Neurology, Sir Charles Gairdner Hospital, Queen Elizabeth II Medical Centre, Perth, Western Australia, Australia
  • ,
  • Allan G. Kermode

      Affiliations

    • Centre for Neuromuscular and Neurological disorders, University of Western Australia, Australia
    • Department of Neurology, Sir Charles Gairdner Hospital, Queen Elizabeth II Medical Centre, Perth, Western Australia, Australia
    • Corresponding Author InformationCorresponding author. Australian Neuromuscular Research Institute, Sir Charles Gairdner Hospital; Centre for Neuromuscular and Neurological Disorders, University of Western Australia, Queen Elizabeth II Medical Centre, 6009, Perth, WA, Australia. Tel.: +61 8 93881865; fax: +61 8 93882149.

Received 17 August 2009 ,Revised 18 October 2009 ,Accepted 15 December 2009.

References 

  1. Horowitz AL, Kaplan RD, Grewe G, et al. The ovoid lesion: a new MR observation in patients with multiple sclerosis. AJNR Am J Neuroradiol. 1989;10:303–305
  2. Miller D. Spectrum of abnormalities in multiple sclerosis. In:  Miller DH Kesselring J,  McDonald WI, et al. editor. Magnetic Resonance in Multiple Sclerosis. Cambridge University Press; 1997;p. 31–62
  3. Seewann A, Enzinger C, Filippi M, et al. MRI characteristics of atypical idiopathic inflammatory demyelinating lesions of the brain: a review of reported findings. J Neurol. 2008;255:1–10
  4. Polman CH, Reingold SC, Edan G, et al. Diagnostic criteria for multiple sclerosis: 2005 revisions to the “McDonald Criteria”. Ann Neurol. 2005;58:840–846
  5. Brainin M, Reisner T, Neuhold A, et al. Topological characteristics of brainstem lesions in clinically definite and clinically probable cases of multiple sclerosis: an MRI-study. Neuroradiology. 1987;29:530–534
  6. Nakashima I, Fujihara K, Okita N, et al. Clinical and MRI study of brain stem and cerebellar involvement in Japanese patients with multiple sclerosis. J Neurol Neurosurg Psychiatry. 1999;67:153–157
  7. Fog T. Topographic distribution of plaques in the spinal cord in multiple sclerosis. Arch Neurol Psychiatry. 1950;63:382–414
  8. Oppenheimer DR. The cervical cord in multiple sclerosis. Neuropathol Appl Neurobiol. 1978;4:151–162
  9. Fog T. On the vessel–plaque relationships in the brain in multiple sclerosis. Acta Neurol Scand Suppl. 1964;40(SUPPL 10):5–9
  10. Kermode AG, Thompson AJ, Tofts P, et al. Breakdown of the blood-brain barrier precedes symptoms and other MRI signs of new lesions in multiple sclerosis. Pathogenetic and clinical implications. Brain. 1990;113:1477–1489
  11. Lumsden C. The neuropathology of multiple sclerosis. In: Handbook of Clinical Neurology. 1970;p. 217–309
  12. Talbert DG. Raised venous pressure as a factor in multiple sclerosis. Med Hypotheses. 2008;70:1112–1117
  13. Zamboni P, Galeotti R, Menegatti E, et al. Chronic cerebrospinal venous insufficiency in patients with multiple sclerosis. J Neurol Neurosurg Psychiatry. 2009;80:392–399
  14. Zamboni P, Menegatti E, Galeotti R, et al. The value of cerebral Doppler venous haemodynamics in the assessment of multiple sclerosis. J Neurol Sci. 2009;282:21–27
  15. Hassler O. Venous anatomy of human hindbrain. A stereomicroangiographic study of the venous angio-architecture and the venous areas of drainage. Arch Neurol. 1967;16:404–409
  16. Stephens R, Stilwell D. Arteries and veins of the human brain. In: Springfield, ILL: Thomas; 1969;p. 165–166
  17. Kim JS, Kim HG, Chung CS. Medial medullary syndrome. Report of 18 new patients and a review of the literature. Stroke. 1995;26:1548–1552

PII: S0022-510X(09)01008-9

doi: 10.1016/j.jns.2009.12.017

Journal of the Neurological Sciences
Volume 290, Issue 1 , Pages 190-193 , 15 March 2010