Journal of the Neurological Sciences
Volume 290, Issue 1 , Pages 57-59 , 15 March 2010

A study of α1 antichymotrypsin gene polymorphism in Indian stroke patients

  • Bindu I Somarajan

      Affiliations

    • Department of Neurology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India
    • ,
  • J. Kalita

      Affiliations

    • Department of Neurology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India
    • ,
  • U.K. Misra

      Affiliations

    • Department of Neurology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India
    • Corresponding Author InformationCorresponding author. Fax: +91 0522 2668017.
    • ,
  • B. Mittal

      Affiliations

    • Department of Genetics, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India

Received 14 September 2009 ,Revised 3 November 2009 ,Accepted 17 November 2009.

References 

  1. Schultz H, Bodeker RH, Damian M, Krack P, Dorndorf W. Age-related spontaneous intracerebral hematoma in a German community. Stroke. 1990;21:1412–1418
  2. Brott T, Thalinger K, Hertzberg V. Hypertension as a risk factor for spontaneous intracerebral hemorrhage. Stroke. 1986;17:1078–1083
  3. Massaro AR, Sacco RL, Mohr JP, Foulkes MA, Tatemichi TK, Price TR, et al. Clinical discriminators of lobar and deep hemorrhages: the Stroke Data Bank. Neurology. 1991;41:1881–1885
  4. Broderick JP, Brott T, Tomsick T, Leach A. Lobar hemorrhage in the elderly: the undiminishing importance of hypertension. Stroke. 1993;24:49–51
  5. Rastenyte D, Tuomilehto J, Sarti C. Genetics of stroke: a review. J Neurol Sci. 1998;153:132–145
  6. Catto AJ, Kohler HP, Bannan S, Stickland M, Carter A, Grant PJ. Factor XIII Val 34 Leu: a novel association with primary intracerebral hemorrhage. Stroke. 1998;29:813–816
  7. O'Donnell HC, Rosand J, Knudsen KA, Furie KL, Segal AZ, Chiu R, et al. Apolipoprotein E genotype and the risk of recurrent lobar intracerebral hemorrhage. N Engl J Med. 2000;342:240–245
  8. Vila N, Obach V, Revilla M, Oliva R, Chamorro A. 1-Antichymotrypsin gene polymorphism in patients with stroke. Stroke. 2000;31:2103–2105
  9. Obach V, Revilla M, Vila N, Chamorro Á. {alpha}1-Antichymotrypsin polymorphism: a risk factor for hemorrhagic stroke in normotensive subjects. Stroke. 2001;32:2588–2591
  10. Fu Y, Xie R, Wang Y, et al. Association between alpha-1-antichymotrypsin gene polymorphism and cerebral hemorrhage. Zhonghua Yi Xue Za Zhi. 2002;82:915–917
  11. Hill MD, Silver FL, Austin PC, Tu JV. Rate of stroke recurrence in patients with primary intracerebral hemorrhage. Stroke. 2000;31:123–127
  12. Miller S, Dykes D. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res. 1988;16:1215–1219
  13. Byth BC, Billingsley GD, Cox DW. Physical and genetic mapping of the serpin cluster at 14q32.1: allelic association and a unique haplotype associated with a1-antichymotrypsin deficiency. Am J Hum Genet. 1994;55:126–133
  14. Fisher CM. Pathological observations in hypertensive cerebral hemorrhage. J Neuropathol Exp Neurol. 1971;30:536–550
  15. Kundsen KA, Rosand J, Karluk D, et al. Clinical diagnosis of cerebral amyloid angiopathy: validation of the Boston criteria. Neurology. 2001;56:537
  16. Ropper AH, Davis KR. Lobar cerebral hemorrhages: acute clinical syndromes in 26 cases. Ann Neurol. 1980;8:141–147
  17. Vinters HV, Duckwiler GR. Intracranial hemorrhage in normotensive elderly patients. Neuroimaging Clin N Am. 1992;2:153–169

PII: S0022-510X(09)00970-8

doi: 10.1016/j.jns.2009.11.009

Journal of the Neurological Sciences
Volume 290, Issue 1 , Pages 57-59 , 15 March 2010

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