Prominent cauda equina involvement in patients with chronic inflammatory demyelinating polyradiculoneuropathy

Matsumoto, Hideyuki; Hanajima, Ritsuko; Terao, Yasuo; Yugeta, Akihiro; Hamada, Masashi; Shirota, Yuichiro; Ohminami, Shinya; Nakatani-Enomoto, Setsu; Tsuji, Shoji; Ugawa, Yoshikazu

doi:10.1016/j.jns.2009.10.014

« Previous Next »Journal of the Neurological Sciences
Volume 290, Issue 1 , Pages 112-114, 15 March 2010

Prominent cauda equina involvement in patients with chronic inflammatory demyelinating polyradiculoneuropathy

Hideyuki Matsumoto
- Department of Neurology, Division of Neuroscience, Graduate School of Medicine, the University of Tokyo, Japan
- Corresponding author. Department of Neurology, Division of Neuroscience, Graduate School of Medicine, the University of Tokyo 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan. Tel.: +81 3 5800 8672; fax: +81 3 5800 6548.
Ritsuko Hanajima
- Department of Neurology, Division of Neuroscience, Graduate School of Medicine, the University of Tokyo, Japan
Yasuo Terao
- Department of Neurology, Division of Neuroscience, Graduate School of Medicine, the University of Tokyo, Japan
Akihiro Yugeta
- Department of Neurology, Division of Neuroscience, Graduate School of Medicine, the University of Tokyo, Japan
Masashi Hamada
- Department of Neurology, Division of Neuroscience, Graduate School of Medicine, the University of Tokyo, Japan
Yuichiro Shirota
- Department of Neurology, Division of Neuroscience, Graduate School of Medicine, the University of Tokyo, Japan
Shinya Ohminami
- Department of Neurology, Division of Neuroscience, Graduate School of Medicine, the University of Tokyo, Japan
Setsu Nakatani-Enomoto
- Department of Neurology, School of Medicine, Fukushima Medical University, Japan
Shoji Tsuji
- Department of Neurology, Division of Neuroscience, Graduate School of Medicine, the University of Tokyo, Japan
Yoshikazu Ugawa
- Department of Neurology, School of Medicine, Fukushima Medical University, Japan

Received 10 August 2009; accepted 13 October 2009. published online 09 November 2009.

Abstract

In chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), it has not been well known which segment of the peripheral nerves, distal or proximal, is more often involved in electrophysiological examination. This study compares nerve conductions at proximal segments with those at distal segments in 11 patients with CIDP. To obtain cauda euqina conduciton time (CECT), compound muscle action potentials (CMAPs) were elicited by magnetic stimulation using a MATS coil from the abductor hallucis muscle. CECT was prolonged in 9 patients (81.8%), whereas the ankle–knee conduction was delayed in 4 (36.4%). The proximal segments are more frequently involved than the distal segments in this disorder.

Keywords: Compound muscle action potential, Electrical stimulation, Magnetic stimulation, Motor evoked potential, Spinal nerve