Prominent cauda equina involvement in patients with chronic inflammatory demyelinating polyradiculoneuropathy
Received 10 August 2009; accepted 13 October 2009. published online 09 November 2009.
Abstract
In chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), it has not been well known which segment of the peripheral nerves, distal or proximal, is more often involved in electrophysiological examination. This study compares nerve conductions at proximal segments with those at distal segments in 11 patients with CIDP. To obtain cauda euqina conduciton time (CECT), compound muscle action potentials (CMAPs) were elicited by magnetic stimulation using a MATS coil from the abductor hallucis muscle. CECT was prolonged in 9 patients (81.8%), whereas the ankle–knee conduction was delayed in 4 (36.4%). The proximal segments are more frequently involved than the distal segments in this disorder.
aDepartment of Neurology, Division of Neuroscience, Graduate School of Medicine, the University of Tokyo, Japan
bDepartment of Neurology, School of Medicine, Fukushima Medical University, Japan
Corresponding author. Department of Neurology, Division of Neuroscience, Graduate School of Medicine, the University of Tokyo 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan. Tel.: +81 3 5800 8672; fax: +81 3 5800 6548.