Journal of the Neurological Sciences
Volume 290, Issue 1 , Pages 115-122 , 15 March 2010

Differential gene expression in chronic inflammatory demyelinating polyneuropathy (CIDP) skin biopsies

  • Grace Lee

      Affiliations

    • Department of Neurology and Neuroscience, Weill Medical College of Cornell University, 525 E. 68th St, New York City, NY 10021, USA
    • Corresponding Author InformationCorresponding author.
    • ,
  • Zhaoying Xiang

      Affiliations

    • Department of Microbiology and Immunology, Weill Medical College of Cornell University, 525 E. 68th St, New York City, NY 10021, USA
    • ,
  • Thomas H. Brannagan III

      Affiliations

    • Neurological Institute, Columbia Presbyterian Medical Center, 710W 168 St, New York City, NY 10021, USA
    • ,
  • Russell L. Chin

      Affiliations

    • Department of Neurology and Neuroscience, Weill Medical College of Cornell University, 525 E. 68th St, New York City, NY 10021, USA
    • ,
  • Norman Latov

      Affiliations

    • Department of Neurology and Neuroscience, Weill Medical College of Cornell University, 525 E. 68th St, New York City, NY 10021, USA

Received 3 July 2009 ,Revised 14 September 2009 ,Accepted 7 October 2009.

References 

  1. Koller H, Kieseier BC, Jander S, Hartung HP. Chronic inflammatory demyelinating polyneuropathy. N Engl J Med. 2005;352:1343–1356
  2. Renaud S, Hays AP, Brannagan TH, et al. Gene expression profiling in chronic inflammatory delyelinating polyeneuropathy. J Neuroimmunol. 2005;159:203–214
  3. Chiang MC, Lin YH, Pan CL, Tseng TJ, Lin LM, Hsieh ST. Cutaneous innervation in chronic inflammatory demyelinating polyneuropathy. Neurology. 2002;59:1094–1098
  4. Ceuterick-de Groote C, De Jonghe P, Timmerman V, et al. Infantile demyelinating neuropathy associated with a de novo point mutation on Ser72 in PMP22 and basal lamina onion bulbs in skin biopsy. Pathol Res Pract. 2001;197:193–198
  5. Lee JE, Shun CT, Hsieh SC, Hsieh ST. Skin denervation in vasculitic neuropathy. Arch Neurol. 2005;62:1570–1573
  6. Li J, Bai Y, Ghandour K, et al. Skin biopsies in myelin-related neuropathies: bringing molecular pathology to the bedside. Brain. 2005;128:1168–1177
  7. Lombardi R, Erne B, Lauria G, et al. IgM deposits on skin nerves in anti-myelin associated glycoprotein neuropathy. Ann Neurol. 2005;57:180–187
  8. Pan CL, Tseng TJ, Lin YH, Chiang MC, Lin WM, Hsieh ST. Cutaneous innervation in Guillain–Barre syndrome: pathology and clinical correlations. Brain. 2003;126:386–397
  9. Chao CC, Hsieh ST, Shun CT, Hsieh SC. Skin denervation and cutaneous vasculitis in eosinophilia-associated neuropathy. Arch Neurol. 2007;64:959–965
  10. Joint Task Force of the EFNS and the PNS . European Federation of Neurologic Societies/Peripheral Nerve Society Guidelines on management of chronic inflammatory demyelinating polyradiculoneuropathy. Report of a joint task force of the European Federation of Neurologic Societies and the Peripheral Nerve Society. J Peripher Nerv Syst. 2005;10:220–228
  11. Shy ME, Garberri JY, Kamholz J. Hereditary motor and sensory neuropathy; a biological perspective. Lancet Neurol. 2002;110–118
  12. Vandesompele J, De Preter K, Pattyn F, Poppe B, Van Roy N, De Paepe A, et al. Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol. 2002;3:research0034.1-0034.11
  13. Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2−DDCt method. Methods. 2001;25:402–408
  14. Younger DS, Rosoklija G, Hays AP, Trojaborg W, Latov N. Diabetic peripheral neuropathy: a clinicopathological and immunohistochemical analysis of sural nerve biopsies. Muscle Nerve. 1996;19:722–727
  15. Rosoklija GB, Dwork AJ, Younger DS, Karlikaya G, Latov N, Hays AP. Local activation of the complement system in endoneurial micorvessels of diabetic neuropathy. Acta Neuropathol. 2000;99:55–62
  16. Liu G, Ma H, Jiang L, Zhao Y. Allograft inflammatory factor-1 and its immune regulation. Autoimmunity. 2007;40:95–102
  17. Orsmark C, Skoog T, Jeskanen L, Kere J, Saarialho-Kere U. Expression of allograft inflammatory factor-1 in inflammatory skin disorders. Acta Derm Venereol. 2007;87:223–227
  18. Schledzewski K, Falkowski M, Moldenhauer G, Metharom P, Kzhyshkowska J, Ganss R, et al. Lymphatic endothelium-specific hyaluronan receptor LYVE-1 is expressed by stabilin-1 +, F4/80 +, CD11b + macrophages in malignant tumours and wound healing tissue in vivo and in bone marrow cultures in vitro: implications for the assessment of lymphangiogenesis. J Pathol. 2006;209:67–77
  19. Peterson EJ. The TCR ADAPts to integrin mediated cell adhesion. Immunol Rev. 2003;192:113–121
  20. Lattin JE, Schroder K, Su AI, Walker JR, Zhang J, Wiltshire T, et al. Expression analysis of G protein-coupled receptors in mouse macrophages. Immunome Res. 2008 Apr 29;4(1):5
  21. Pina C, May G, Soneji S, Hong D, Enver T. MLLT3 regulates early human erythroid and megakaryocytic cell fate. Cell Stem Cell. 2008;2:264–273
  22. Hogerkorp AM, Bilke S, Breslin T, Ingarsson S, Borrebaeck CA. CD44-stimulated human B cells express transcripts specifically involved in immunomodulation and inflammation as analyzed by DNA microarrays. Blood. 2003;101:2307–2313
  23. Pramparo T, Grosso S, Messa J, Zatterale A, Bonaglia MC, Chessa L, et al. Loss-of-function mutation of the AF9/MLLT3 gene in a girl with neuromotor development delay, cerebellar ataxia, and epilepsy. Hum Genet. 2005;118:76–81
  24. Broqlio L, Erne B, Tolnay M, Schaeren-Wiemers N, Fuhr P, Steck AJ, et al. Allograft inflammatory factor-1; a pathogenic factor for vasculitic neuropathy. Muscle Nerve. 2008;38:1272–1279
  25. Chi LJ, Wang HB, Wang WZ. Impairment of circulating CD4+CD25+ regulatory T cells in patients with chronic inflammatory demyelinating polyradiculoneuropathy. J Peripher Nerv Syst. 2008;13:54–63
  26. Tackenberg B, Jelcic I, Baerenwaldt A, Gertel WH, Sommer N, Nimmerjahn F, et al. Impaired inhibitory Fcgamma receptor IIB expression on B-cells in chronic inflammatory demyelinating polyneuropathy. Proc Natl Acad Sci. 2009;106:4788–4792
  27. Comi C, Osio M, Ferretti M, Mesturini R, Cappellano G, Chiocchetti A, et al. Defective FAS-mediated T-cell apoptosis predicts acute onset CIDP. J Peripher Nerv Syst. 2009;14:101–106
  28. Haq RU, Pendlebury WW, Fries TJ, Tandan R. Chronic inflammatory polyradiculoneuropathy in diabetic patients. Muscle Nerve. 2003;27:465–470
  29. Ginsberg L, Malik O, Kenton AR, Sharp D, Muddle JR, Davis MB, et al. Coexistent hereditary and inflammatory neuropathy. Brain. 2004;127:193–202

PII: S0022-510X(09)00902-2

doi: 10.1016/j.jns.2009.10.006

Journal of the Neurological Sciences
Volume 290, Issue 1 , Pages 115-122 , 15 March 2010

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