Journal of the Neurological Sciences
Volume 288, Issue 1 , Pages 13-24, 15 January 2010

Penumbra, the basis of neuroimaging in acute stroke treatment: Current evidence

  • Gyanendra Kumar

      Affiliations

    • Department of Neurology, University of Missouri-Healthcare Columbia, Columbia, CE 507 Five Hospital Drive, Columbia, Missouri, 65212, USA
    • Corresponding Author InformationCorresponding author. Tel.: +1 573 882 4141; fax: +1 573 884 4249.
    • ,
  • Munish Kumar Goyal

      Affiliations

    • Department of Neurology, University of Missouri-Healthcare Columbia, Columbia, CE 507 Five Hospital Drive, Columbia, Missouri, 65212, USA
    • ,
  • Pradeep Kumar Sahota

      Affiliations

    • Department of Neurology, University of Missouri-Healthcare Columbia, Columbia, CE 507 Five Hospital Drive, Columbia, Missouri, 65212, USA
    • ,
  • Rajan Jain

      Affiliations

    • Department of Radiology, Division of Neuroradiology, Henry Ford Hospital, Detroit, Michigan, USA

Received 12 June 2009; received in revised form 6 August 2009; accepted 23 September 2009. published online 30 October 2009.

Abstract 

In modern medicine brain imaging is an essential prerequisite not only to acute stroke triage but also to determining the specific therapy indicated. This article reviews the need for imaging the brain in acute stroke, penumbral pathophysiology, penumbral imaging techniques, as well as current status of various imaging modalities that are being employed to select patients for specific therapeutic approaches.

Keywords: Acute stroke, Thrombolysis, Penumbra, Neuroimaging

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PII: S0022-510X(09)00870-3

doi:10.1016/j.jns.2009.09.027

Journal of the Neurological Sciences
Volume 288, Issue 1 , Pages 13-24, 15 January 2010

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