Journal of the Neurological Sciences
Volume 280, Issue 1 , Pages 109-110 , 15 May 2009

Prulifloxacin as a trigger of myasthenia gravis

  • Marco Rossi

      Affiliations

    • Department of Pharmacology “Giorgio Segre”, University of Siena, Siena, Italy
    • Tuscan Center for Pharmacovigilance, University of Siena, Siena, Italy
    • Corresponding Author InformationCorresponding author. Department of Pharmacology “Giorgio Segre”, University of Siena, Strada delle Scotte,6 — 53100 Siena, Italy. Tel.: +39 0577586406; fax: +39 0577233102.
    • ,
  • Gaia Lusini

      Affiliations

    • Tuscan Center for Pharmacovigilance, University of Siena, Siena, Italy
    • ,
  • Alessia Biasella

      Affiliations

    • Section of Clinical Neurophysiology, Department of Neurological, Neurosurgical and Behavioral, Sciences, University of Siena, Siena, Italy
    • ,
  • Riccardo Mazzocchio

      Affiliations

    • Section of Clinical Neurophysiology, Department of Neurological, Neurosurgical and Behavioral, Sciences, University of Siena, Siena, Italy

Received 24 November 2008 ,Accepted 28 January 2009.

References 

  1. http://www.myasthenia.org/docs/MGFA_MedicationsandMG.pdf. Accessed 16 October 2008.
  2. Moore B, Safani M, Keesey J. Possible exacerbation of myasthenia gravis by ciprofloxacin. Lancet. 1988;1(8590):882
  3. Rauser EH, Ariano RE, Anderson BA. Exacerbation of myasthenia gravis by norfloxacin. DICP. 1990;24(2):207–208
  4. Mumford CJ, Ginsberg L. Ciprofloxacin and myasthenia gravis. BMJ. 1990;301(6755):818
  5. Azevedo E, Ribeiro JA, Polónia J, Pontes C. Probable exacerbation of myasthenia gravis by ofloxacin. J Neurol. 1993;240(8):508
  6. Vial T, Chauplannaz G, Brunel P, Leriche B, Evreux JC. [Exacerbation of myasthenia gravis by pefloxacin]. Rev Neurol (Paris). 1995;151(4):286–287
  7. Roquer J, Cano A, Seoane JL, Pou Serradell A. Myasthenia gravis and ciprofloxacin. Acta Neurol Scand. 1996;94(6):419–420
  8. Gunduz A, Turedi S, Kalkan A, Nuhoglu I. Levofloxacin induced myasthenia crisis. Emerg Med J. 2006;23(8):662
  9. Sieb JP, Milone M, Engel AG. Effects of the quinoline derivatives quinine, quinidine, and chloroquine on neuromuscular transmission. Brain Res. 1996;18;712(2):179–189
  10. Sieb JP. Fluoroquinolone antibiotics block neuromuscular transmission. Neurology. 1998;50(3):804–807

PII: S0022-510X(09)00047-1

doi: 10.1016/j.jns.2009.01.019

Journal of the Neurological Sciences
Volume 280, Issue 1 , Pages 109-110 , 15 May 2009

Article Tools