Journal of the Neurological Sciences
Volume 280, Issue 1 , Pages 109-110, 15 May 2009

Prulifloxacin as a trigger of myasthenia gravis

  • Marco Rossi

      Affiliations

    • Department of Pharmacology “Giorgio Segre”, University of Siena, Siena, Italy
    • Tuscan Center for Pharmacovigilance, University of Siena, Siena, Italy
    • Corresponding Author InformationCorresponding author. Department of Pharmacology “Giorgio Segre”, University of Siena, Strada delle Scotte,6 — 53100 Siena, Italy. Tel.: +39 0577586406; fax: +39 0577233102.
    • ,
  • Gaia Lusini

      Affiliations

    • Tuscan Center for Pharmacovigilance, University of Siena, Siena, Italy
    • ,
  • Alessia Biasella

      Affiliations

    • Section of Clinical Neurophysiology, Department of Neurological, Neurosurgical and Behavioral, Sciences, University of Siena, Siena, Italy
    • ,
  • Riccardo Mazzocchio

      Affiliations

    • Section of Clinical Neurophysiology, Department of Neurological, Neurosurgical and Behavioral, Sciences, University of Siena, Siena, Italy

Received 24 November 2008; accepted 28 January 2009. published online 23 February 2009.

Abstract 

Fluoroquinolones has been rarely associated with exacerbation of myasthenia gravis (MG). We present a case of MG following a treatment with prulifloxacin, a new broad-spectrum oral fluoroquinolone. Fluoroquinolones of any generation may interfere with neuromuscular transmission and should be avoided in patients with MG.

Keywords: Fluoroquinolones/adverse effects, Prulifloxacin, Myasthenia gravis

To access this article, please choose from the options below

Login to an existing account or Register a new account.

  • Purchase this article for 31.50 USD (You must login/register to purchase this article)

    Online access for 24 hours. The PDF version can be downloaded as your permanent record.

  • Subscribe to this title

    Get unlimited online access to this article and all other articles in this title 24/7 for one year.

  • Claim access now

    For current subscribers with Society Membership or Account Number.

  • Visit SciVerse ScienceDirect to see if you have access via your institution.
 

PII: S0022-510X(09)00047-1

doi:10.1016/j.jns.2009.01.019

Journal of the Neurological Sciences
Volume 280, Issue 1 , Pages 109-110, 15 May 2009

Article Tools