« Previous
Next »
Journal of the Neurological Sciences
Volume 238, Issue 1
, Pages 53-57
, 15 November 2005
Lymphocyte-specific protein tyrosine kinase is a novel risk gene for Alzheimer disease
References
- . Gene-environment interaction in Alzheimer's disease: a potential role for cholesterol. Neuroepidemiology. 1998;17:225–232
- . The epidemiology of dementia and Alzheimer disease. In: Terry RD, Katzman R, Bick KL, Sisodia SS editor. Alzheimer disease. 2nd ed.. Philadelphia: Lippincott Williams & Wilkins; 1999;p. 95–116
- . Alzheimer's disease: genes, proteins, and therapy. Physiol Rev. 2001;81:741–766
- . The importance of inflammatory mechanisms in Alzheimer's disease. Exp Gerontol. 1998;33:371–378
- . Chemokines/chemokine receptors in the central nervous system and Alzheimer's disease. J Neurovirol. 1999;5:32–41
- Occurrence of T cells in the brain of Alzheimer's disease and other neurological diseases. J Neuroimmunol. 2002;124:83–92
- CCR2-64I polymorphism and CCR5Delta32 deletion in patients with Alzheimer's disease. J Neurol Sci. 2004;225:79–83
- . Requirement for association of p56lck with CD4 in antigen-specific signal transduction in T cells. Cell. 1991;64:511–520
- . Src-related protein tyrosine kinases and T-cell receptor signaling. Trends Genet. 1992;8:61–66
- . Regulation of src family tyrosine kinases in lymphocytes. Trends Biochem Sci. 1993;18:215–220
- The Lck tyrosine kinase is expressed in brain neurons. J Neurochem. 1996;67:1360–1364
- . Expression of a novel form of the p56lck protooncogene in rat cerebellar granular neurons. J Neurochem. 1996;67:2306–2315
- Up-regulation of calcineurin Abeta mRNA in the Alzheimer's disease brain: assessment by cDNA microarray. Biochem Biophys Res Commun. 2001;284:310–316
- Results of a high-resolution genome screening of 437 Alzheimer's disease families. Hum Mol Genet. 2003;12:23–32
- . Two lck transcripts containing different 5′ untranslated regions are present in T cells. Mol Cell Biol. 1987;7:4407–4413
- No association between lck gene polymorphisms and protein level in type 1 diabetes. Diabetes. 2002;51:3326–3330
- . Oncogenic activation of the LCK protein accompanies translocation of the LCK gene in the human HSB2 T-cell leukemia. Mol Cell Biol. 1994;14:2429–2437
- Specific deficiency of p56lck expression in T lymphocytes from type 1 diabetic patients. J Immunol. 2000;165:5874–5883
- Dysregulation of p56lck kinase in patients with systemic lupus erythematosus. Autoimmunity. 2001;34:27–38
- In vivo gene expression revealed by cDNA arrays: the pattern in relapsing–remitting multiple sclerosis patients compared with normal subjects. J Neuroimmunol. 2001;116:213–219
- . A potential role for protein tyrosine kinase p56(lck) in rheumatoid arthritis synovial fluid T lymphocyte hyporesponsiveness. Int Immunol. 2001;13:305–312
- . Expression of the p56lck by colon tumors: a marker of their invasive capacity?. Bull Cancer. 2004;91:928–940
- Association analysis of the lymphocyte-specific protein tyrosine kinase (LCK) gene in type 1 diabetes. Diabetes. 2004;53:2479–2482
- . Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's disease. Neurology. 1984;34:939–944
- . ‘Mini-mental state’. A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975;12:189–198
- Genetic association between Alzheimer disease and the alpha-synuclein gene. Dement Geriatr Cogn Disord. 2001;12:106–109
- Subtype analysis of neuropathologically diagnosed patients in a Japanese geriatric hospital. J Neurol Sci. 2002;196:63–69
- . In: Molecular cloning: a laboratory manual. 2nd ed.. New York: Cold Spring Harbor Laboratory Press; 1989;p. 9.14–9.19
- . Identification of a novel repressive element in the proximal lck promoter. J Biol Chem. 1995;270:27538–27543
- . A thousand and one protein kinases. Cell. 1987;50:823–829
- . Neural tissues express high levels of the cellular src gene product pp60c-src. Mol Cell Biol. 1983;3:1157–1162
- . Src, N-methyl-d-aspartate (NMDA) receptors, and synaptic plasticity. Biochem Pharmacol. 1998;56:789–798
- . Impaired long-term potentiation, spatial learning, and hippocampal development in fyn mutant mice. Science. 1992;258:1903–1910
- . Scr family kinases control neural development and function. Dev Growth Differ. 1994;36:543–550
- . NMDA receptor regulation by Src kinase signalling in excitatory synaptic transmission and plasticity. Curr Opin Neurobiol. 2001;11:336–342
- . Src activation in the induction of long-term potentiation in CA1 hippocampal neurons. Science. 1998;279:1363–1367
- . NMDA channel regulation by channel-associated protein tyrosine kinase Src. Science. 1997;275:674–678
- . Specific coupling of NMDA receptor activation to nitric oxide neurotoxicity by PSD-95 protein. Science. 1999;284:1845–1848
PII: S0022-510X(05)00262-5
doi: 10.1016/j.jns.2005.06.017
© 2005 Elsevier B.V. All rights reserved.
« Previous
Next »
Journal of the Neurological Sciences
Volume 238, Issue 1
, Pages 53-57
, 15 November 2005
