Journal of the Neurological Sciences
Volume 226, Issue 1 , Pages 49-52 , 15 November 2004

Facts, myths, and controversies in vascular dementia

  • Gustavo C. Román

      Affiliations

    • Corresponding Author InformationMedicine/Neurology, University of Texas HSC at San Antonio, TX 78232, USA. Tel.: +1 210 617 5161; fax: +1 210 567 4659.

References 

  1. Jorm AF, O'Brien J. The epidemiology of vascular dementia: an overview and commentary. In:  O'Brien J,  Ames D,  Gustafson L,  Folstein M,  Chiu E editor. Cerebrovascular disease, cognitive impairment and dementia. 2nd ed.. London: Martin Dunitz; 2004;p. 95–100
  2. Román GC, Tatemichi TK, Erkinjuntti T, Cummings JL, Masdeu JC, Garcia JH , et al. Vascular dementia: diagnostic criteria for research studies. Report of the NINDS-AIREN International Workshop. Neurology. 1993;43:250–260
  3. Chui HC, Victoroff JI, Margolin D, Jagust W, Shankle R, Katzman R. Criteria for the diagnosis of ischemic vascular dementia proposed by the state of California Alzheimer's Disease diagnostic and treatment centers. Neurology. 1992;42:473–480
  4. Rocca WA, Hofman A, Brayne C, Breteler MM, Clarke M, Copeland JR, et al. The prevalence of vascular dementia in Europe: facts and fragments from 1980–1990 studies. Ann. Neurol. 1991;30:817–824
  5. Lobo A, Launer LJ, Fratiglioni L, Andersen K, DiCarlo A, Breteler MMB, et al. Prevalence of dementia and major subtypes in Europe: a collaborative study of population-based cohorts. Neurology. 2000;54(Suppl. 5):4–9
  6. Ikeda M, Hokoishi K, Maki N, Nebu A, Tachibana N, Komori K, et al. Increased prevalence of vascular dementia in Japan: a community-based epidemiological study. Neurology. 2001;57:839–844
  7. Pohjasvaara T, Erkinjuntti T, Vataja R, Kaste M. Dementia three months after stroke. Baseline frequency and effect of different definitions of dementia in the Helsinki stroke aging memory study (SAM) cohort. Stroke. 1997;28:785–792
  8. Barba R, Martínez-Espinosa S, Rodríguez-García E, Pondal M, Vivancos J, Del Ser T. Poststroke dementia. Clinical features and risk factors. Stroke. 2000;31:1494–1501
  9. Hachinski VC, Lassen NA, Marshall J. Multi-infarct dementia: a cause of mental deterioration in the elderly. Lancet. 1974;2:207–210
  10. Román GC. Senile dementia of the Binswanger type: a vascular form of dementia in the elderly. JAMA. 1987;258:1782–1788
  11. Román GC. From UBOs to Binswanger's disease. Impact of MRI on VaD research. Stroke. 1996;27:1269–1273
  12. Román GC. A historical evolution of the concept of dementia: a systematic review from 2000 BC to 2000 AD. In:  Qizilbash N editors. Evidence-based Dementia management. London: Blackwell Science; 2002;
  13. Royall DR. Executive cognitive impairment: a novel perspective on dementia. Neuroepidemiology. 2000;1:293–299
  14. Royall DR, Cabello M, Polk MJ. Executive dyscontrol: an important factor affecting the level of care received by older retirees. J. Am. Geriatr. Soc. 1998;46:1519–1524
  15. Pohjasvaara T, Leskelä M, Vataja R, Kalska H, Ylikoski R, Hietanen M, et al. Post-stroke depression, executive dysfunction and functional outcome. Eur. J. Neurol. 2002;9:269–275
  16. Cummings JL. Vascular subcortical dementias: clinical aspects. Dementia. 1994;5:177–180
  17. Desmond DW, Erkinjuntti T, Sano M, Cummings JL, Bowler JV, Pasquier F, et al. The cognitive syndrome of vascular dementia: implications for clinical trials. Alzheimer Dis. Assoc. Disord. 1999;13(Suppl. 3):S21–S29
  18. Román GC, Erkinjuntti T, Wallin A, Pantoni L, Chui HC. Subcortical ischaemic VaD. Lancet Neurol. 2002;1:426–436
  19. Braak H, Braak E. Frequency of stages of Alzheimer-related lesions in different age categories. Neurobiol. Aging. 1997;18:351–357
  20. Duyckaerts C, Hauw J-J. Prevalence, incidence and duration of Braak's stages in the general population: can we know?. Neurobiol. Aging. 1997;18:362–369
  21. Looi JCL, Sachdev PS. Differentiation of vascular dementia from AD on neuropsychological tests. Neurology. 1999;53:670–678
  22. Petersen RC, Smith GE, Waring SC, Ivnik RJ, Tangalos EG, Kokmen E. Mild cognitive impairment: clinical characterization and outcome. Arch. Neurol. 1999;56:303–308
  23. Román GC, Royall DR. Executive control function: a rational basis for the diagnosis of vascular dementia. Alzheimer Dis. Assoc. Disord. 1999;13(Suppl. 3):S69–S80
  24. Kalaria RN, Ballard C. Overlap between pathology of Alzheimer disease and vascular dementia. Alzheimer Dis. Assoc. Disord. 1999;13(Suppl. 3):S115–S123
  25. Tohgi H, Abe T, Kimura M, Saheki M, Takahashi S. Cerebrospinal fluid acetylcholine and choline in vascular dementia of Binswanger and multiple small infarct types as compared with Alzheimer-type dementia. J. Neural. Trans. 1996;103:1211–1220
  26. Gottfries CG, Blennow K, Karlsson I, Wallin A. The neurochemistry of vascular dementia. Dementia. 1994;5:163–167
  27. Wallin A, Blennow K, Gottfries CG. Neurochemical abnormalities in vascular dementia. Dementia. 1989;1:120–130
  28. Szilagyi AK, Nemeth A, Martini E, Lendvai B, Venter V. Serum and CSF cholinesterase activity in various kinds of dementia. Eur. Arch. Psychiatr. Neurol. Sci. 1987;236:309–311
  29. Swartz RH, Sahlas DJ, Black SE, et al. Strategic involvement of cholinergic pathways and executive dysfunction: does location of white matter signal hyperintensity matter?. J. Stroke CVD. 2003;12:29–36
  30. Selden NR, Gitelman DR, Salamon-Murayama N, et al. Trajectories of cholinergic pathways within the cerebral hemispheres of the human brain. Brain. 1998;121:2249–2257
  31. Mesulam M, Siddique T, Cohen B. Cholinergic denervation in a pure multi-infarct state: observations on CADASIL. Neurology. 2003;60:1183–1185
  32. Sato A, Sato Y, Uchida S. Regulation of regional cerebral blood flow by cholinergic fibers originating in the basal forebrain. Int. J. Dev. Neurosci. 2001;1:327–337
  33. Biesold D, Inanami O, Sato A, Sato Y. Stimulation of the nucleus basalis of Meynert increases cerebral cortical blood flow in rats. Neurosci. Lett. 1989;98:39–44
  34. Court JA, Perry EK, Kalaria RN. Neurotransmitter control of the cerebral vasculature and abnormalities in vascular dementia. In:  Erkinjuntti T,  Gauthier S editor. Vascular cognitive impairment. London: Martin Duniz; 2002;p. 167–185

PII: S0022-510X(04)00292-8

doi: 10.1016/j.jns.2004.09.011

Journal of the Neurological Sciences
Volume 226, Issue 1 , Pages 49-52 , 15 November 2004