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Journal of the Neurological Sciences
Volume 222, Issue 1
, Pages 13-19
, 15 July 2004
High-dose, frequently administered interferon beta therapy for relapsing–remitting multiple sclerosis must be maintained over the long term: the interferon beta dose-reduction study
References
- Intramuscular interferon beta-1a for disease progression in relapsing multiple sclerosis. Ann. Neurol. 1996;39:285–294
- . Interferon beta-1b is effective in relapsing–remitting multiple sclerosis. I: clinical results of a multicenter, randomized, double-blind, placebo-controlled trial. Neurology. 1993;43:655–661
- . Randomized, double-blind, placebo-controlled study of interferon beta-1a in relapsing–remitting multiple sclerosis. Lancet. 1998;352:1498–1504
- . Rating neurological impairment in multiple sclerosis: an expanded disability status scale (EDSS). Neurology. 1983;33:1444–1452
-
.
Interferon beta-1b in the treatment of multiple sclerosis: final outcome of the randomized controlled trial.
Neurology. 1995;45:177–185
- The effect of interferon-β on blood–brain barrier disruptions demonstrated by contrast-enhanced magnetic resonance imaging in relapsing remitting multiple sclerosis. Ann. Neurol. 1995;37:611–619
- Characterization of MRI response to treatment with interferon beta-1b: contrast enhancing MRI lesion frequency as primary outcome measures. Neurology. 1997;49:862–869
- Guidelines for use of magnetic resonance techniques in monitoring the treatment of multiple sclerosis. Ann. Neurol. 1996;39:6–16
- Immunoregulatory effects of interferon-beta and interacting cytokines on human vascular endothelial cells. Implications for multiple sclerosis and other autoimmune diseases. J. Neuroimmunol. 1996;64:151–161
- Incidence and significance of neutralizing antibodies to interferon beta-1a in multiple sclerosis. The Multiple Sclerosis Collaborative Research Group (MSCRG). Neurology. 1998;50:1266–1272
- Every-other-day interferon beta-1b versus once-a-weekly interferon beta-1a for multiple sclerosis: results of a 2-year prospective randomized multicentre study (INCOMIN). Lancet. 2001;359:1453–1460
- Randomized, comparative study of interferon beta-1a treatment regimens in MS. The EVIDENCE Trial. Neurology. 2002;59:1496–1506
- New diagnostic criteria for multiple sclerosis: guidelines for research protocols. Ann. Neurol. 1983;13:227–231
- Development of neutralizing antibodies in patients with relapsing remitting multiple sclerosis treated with IFN beta-1a. J. Interferon Cytokine Res. 1998;18:345–350
- . Magnetic resonance imaging lesion enlargement in multiple sclerosis. Disease-related activity, chance occurrence or measurement artifact?. Arch. Neurol. 1992;49:261–263
- Effect of training and different measurement strategies on the reproducibility of brain MRI lesion load measurements in multiple sclerosis. Neurology. 1998;50:238–244
- . Semiautomated thresholding technique for measuring lesion volumes in multiple sclerosis: effects of the change of the threshold on the computed lesion loads. Acta Neurol. Scand. 1996;93:30–34
- . Incidence of exacerbations in the first 90 days of treatment with recombinant human interferon beta-1b in patients with relapsing–remitting multiple sclerosis. Ann. Neurol. 1998;44:138–139
- Evidence of interferonβ-1a dose response in relapsing–remitting MS. The OWIMS Study. The Once Weekly Interferon for MS Study Group. Neurology. 1999;53:679–686
-
.
Interferon in relapsing–remitting multiple sclerosis (Cochrane review).
In: The Cochrane Library, Issue 4. Oxford: Update Software; 2001;p. 853–863
- Interferon beta-1b decreases the migration of T lymphocytes in vitro: effects on matrix metalloproteinase-9. Ann. Neurol. 1996;40:853–863
- . Interferon beta-1b inhibits gelatinase secretion and in vitro migration of human T-cells: a possible mechanism for treatment efficacy in multiple sclerosis. Ann. Neurol. 1996;40:846–852
- Comparative pharmacodynamics of two recombinant human interferon beta-1a (IFNβ-1a) products administered intramuscularly in healthy male and female volunteers. Pharm. Res. 1997;14:546–549
- . Pharmacodynamic comparison of single doses of IFNβ-1a and IFNβ-1b in healthy volunteers. J. Interferon Cytokine Res. 1999;19:1257–1264
- . A phase I study of recombinant interferon beta in patients with advanced malignant disease. Clin. Cancer Res. 1999;5:3990–3998
- . Effects on interferon beta on non-A, non-B acute hepatitis: a prospective, randomized, controlled-dose study. Gastroenterology. 1994;107:805–811
- Heterogeneity of blood–brain barrier changes in multiple sclerosis: an MRI study with gadolinium-DTPA enhancement. Neurology. 1990;40:229–235
- Using gadolinium-enhanced magnetic resonance imaging lesions to monitor disease activity in multiple sclerosis. Ann. Neurol. 1992;32:758–766
- Predictive value of gadolinium-enhanced magnetic resonance imaging for relapse rate and change in disability or impairment in multiple sclerosis: a meta-analysis. Lancet. 1999;353:964–969
- . T2 hyperintensities: findings and significance. Neuroimaging Clin. N. Am. 2000;10:717–738
PII: S0022-510X(04)00091-7
doi: 10.1016/j.jns.2004.03.023
© 2004 Elsevier B.V. All rights reserved.
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Journal of the Neurological Sciences
Volume 222, Issue 1
, Pages 13-19
, 15 July 2004
