Journal of the Neurological Sciences
Volume 215, Issue 1 , Pages 27-29 , 15 November 2003

Absence of detection of Varicella-Zoster virus DNA in temporal artery biopsies obtained from patients with giant cell arteritis

  • Peter G.E. Kennedy

      Affiliations

    • Corresponding Author InformationCorresponding author. Tel.: +44-141-201-2474; fax: +44-141-201-2993.
    • Department of Neurology, Institute of Neurological Sciences, Southern General Hospital, Govan Road, Glasgow G51 4TF, UK
    • ,
  • Esther Grinfeld

      Affiliations

    • Department of Neurology, Institute of Neurological Sciences, Southern General Hospital, Govan Road, Glasgow G51 4TF, UK
    • ,
  • Margaret M. Esiri

      Affiliations

    • Department of Neurology, University of Oxford, Radcliffe Infirmary, Oxford OX2 6HE, UK

Received 7 April 2003 ,Revised 20 May 2003 ,Accepted 20 May 2003.

References 

  1. Gilden DH, Kleinschmidt-DeMasters BK, LaGuardia JJ, Mahalingam R, Cohrs RJ. Medical progress: neurologic complications of the reactivation of Varicella-Zoster virus. N. Engl. J. Med. 2000;342:635–646
  2. Kennedy PGE. Varicella-Zoster virus latency in human ganglia. Rev. Med. Virol. 2002;12:327–334
  3. Mitchell BM, Font RL. Detection of Varicella Zoster virus DNA in some patients with giant cell arteritis. Invest. Ophthalmol. Vis. Sci. 2002;42:2572–2577
  4. Nordborg C, Nordborg E, Petursdottir V, LaGuardia J, Mahalingam R, Wellish M, et al.  Search for Varicella Zoster virus in giant cell arteritis. Ann. Neurol. 1998;44:413–414
  5. Helweg-Larsen J, Tarp B, Obel N, Baslund B. No evidence of parvovirus B19, Chlamydia pneumoniae or human herpes virus infection in temporal artery biopsies in patients with giant cell arteritis. Rheumatology. 2002;41:445–449
  6. Dahaut P, Bosshard S, Calvet A, Pinede L, Demolombe-Rague S, Dumontet C, et al.  Giant cell arteritis, polymylagia rheumatica, and viral hypotheses: a multicenter, prospective case-control study. Groupe de Recherche sur l'Arterite a Cellules Geantes. J. Rheumatol. 1999;26:361–369
  7. Kennedy PGE, Grinfeld E, Gow JW. Latent Varicella-Zoster virus is located predominantly in neurons in human trigeminal ganglia. Proc. Natl. Acad. Sci. U. S. A. 1998;95:4658–4662
  8. Kennedy PGE, Grinfeld E, Bontems S, Sadzot-Delvaux C. Varicella-Zoster virus gene expression in latently infected rat dorsal root ganglia. Virology. 2001;289:218–223
  9. Ruth L. Probing questions about in situ PCR. Alkami Biosystems: PCR Reviews; 1998. December.

PII: S0022-510X(03)00167-9

doi: 10.1016/S0022-510X(03)00167-9

Journal of the Neurological Sciences
Volume 215, Issue 1 , Pages 27-29 , 15 November 2003

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