Journal of the Neurological Sciences
Volume 213, Issue 1 , Pages 35-45 , 15 September 2003

The effect of transcranial magnetic stimulation over the cerebellum on the synkinesis of coordinated eye and head movements

  • M Nagel

      Affiliations

    • Department of Psychiatry, University Hospital Lübeck, Ratzeburger Allee 160, 23562 Lübeck, Germany
    • Tel.: +49-451-5000.
  • ,
  • W.H Zangemeister

      Affiliations

    • Corresponding Author InformationCorresponding author. Tel.: +49-40-42803-2607; fax: +49-40-42803-2784.
    • Department of Neurology, University Hospital Hamburg Eppendorf, Martinistrasse 52, 20251 Hamburg, Germany

Received 23 December 2002 ,Revised 20 March 2003 ,Accepted 28 April 2003.

References 

  1. Bahill AT, Adler D, Stark L. Most naturally occurring human saccades have magnitudes of 15 degrees or less. Invest. Ophthalmol. 1975;14:468–469
  2. Zangemeister WH, Stark L. Active head rotations and eye–head coordination. Ann. N. Y. Acad. Sci. 1981;374:540–559
  3. Bizzi E, Kalil RE, Tagliasco V. Eye–head coordination in monkeys: evidence for centrally patterned organization. Science. 1971;173:452–454
  4. Bizzi E. The coordination of eye–head movements. Sci. Am. 1974;231:100–106
  5. Barnes GR. Head–eye coordination in normals and in patients with vestibular disorders. Adv. Oto-rhino-laryngol. 1979;25:197–201
  6. Zangemeister WH, Stark L. Gaze latency: variable interactions of head and eye latency. Exp. Neurol. 1982;75:389–406
  7. Zangemeister WH, Stark L. Types of gaze movement: variable interactions of eye and head movements. Exp. Neurol. 1982;77:563–577
  8. Moschner C, Zangemeister WH. Preview control of gaze saccades: efficacy of prediction modulates eye–head interaction during human gaze saccades. Neurol. Res. 1993;15:417–432
  9. Stahl JS. Amplitude of human head movements associated with horizontal saccades. Exp. Brain Res. 1999;126:41–54
  10. Baloh R, Demer J. Optokinetic-vestibular interaction in patients with increased gain of the vestibulo-ocular reflex. Exp. Brain Res. 1993;97:334–342
  11. Ohtsuka K, Noda H. The effect of microstimulation of the oculomotor vermis on discharges of fastigial neurons and visually directed saccades macaques. Neurosci. Res. 1991;10:290–295
  12. Ohtsuka K, Noda H. Discharge properties of Purkinje cells in the oculomotor vermis during visually guided saccades in the macaque monkey. J. Neurophysiol. 1995;74:1828–1840
  13. Noda H, Fujikado T. Topography of the oculomotor area of the cerebellar vermis in macaques as determined by microstimulation. J. Neurophysiol. 1987;58:359–378
  14. Fujikado T, Noda H. Oculomotor responses to microstimulation of the posterior cerebellar vermis in the monkey. Soc. Neurosci. Abstr. 1984;10:752
  15. Goffart L, Guillaume A, Pélisson D. Compensation for gaze pertubation during inactivation of the caudal fastigial nucleus in the head-unrestrained cat. J. Neurophysiol. 1998;80:1552–1557
  16. Pellison D, Goffart L, Guillaume A. Contribution of the rostral fastigial nucleus to the control of orienting gaze shift in the head-unrestrained cat. J. Neurophysiol. 1998;80:1180–1196
  17. Vidal PP, Roucoux A, Berthoz A. Horizontal eye position-related activity in neck muscles of the alert cat. Exp. Brain Res. 1982;46:448–453
  18. Oechsner M, Zangemeister WH. Prolonged postexcitatory inhibition after transcranial magnetic stimulation of the motor cortex in patients with cerebellar ataxia. J. Neurol. Sci. 1999;168:107–111
  19. Hashimoto M, Ohtsuka K. Transcranial magnetic stimulation over the posterior cerebellum during visually guided saccades in man. Brain. 1995;118:1185–1193
  20. Ohtsuka K, Enoki T. Transcranial magnetic stimulation over the posterior cerebellum during smooth pursuit in man. Brain. 1998;121:429–435
  21. Faust U, Liu J, Zangemeister WH. Current distribution in the electrolytically conducting half space in magnetic stimulation. Biomed. Tech. (Berl.). 1990;35(Suppl. 3):164–165
  22. Werhahn KJ, Taylor J, Ridding M, Meyer BU, Rothwell JC. Effect of transcranial magnetic stimulation over the cerebellum on the excitability of human motor cortex. Electroencephalogr. Clin. Neurophysiol. 1996;101:b58–b66
  23. Ugawa Y, Uesaka Y, Terao Y, Hanajima R, Kanazawa I. Magnetic stimulation over the cerebellum in humans. Ann. Neurol. 1995;37:703–713
  24. Ugawa Y, Terao Y, Hanajima R, Sakai K, Furubayashi T, Machii K, et al.  Magnetic stimulation over the cerebellum in patients with ataxia. Electroencephalogr. Clin. Neurophysiol. 1997;104:453–458
  25. Brandt SA, Ploner CJ, Meyer BU, Leistner S, Villringer A. Effects of repetitive transcranial magnetic stimulation over the dorsolateral prefrontal and posterior parietal cortex on memory guided saccades. Exp. Brain Res. 1998;118:197–204
  26. Meyer BU, Diehl R, Steinmetz H, Cornelius-Britton T, Benecke R. Magnetic stimuli applied over motor and visual cortex: Influence of coil position and field polarity on motor responses, Phosphenes and eye movements. Electroencephalogr. Clin. Neurophysiol. 1991;43:121–134 [suppl.]
  27. Muri RM, Rivaud S, Gaymard B, Ploner CJ, Vermersch AI, Hess CW, et al.  Role of the prefrontal cortex in the control of express saccades. A transcranial magnetic stimulation study. Neuropsychologia. 1999;37:199–206
  28. Isotalo E, Pyykkö I, Juhola M, Aalto H. Pseudo random smooth pursuit test in patients with acoustic neuroma. Acta Oto-laryngol (Stockholm). 1995;520:295–297 [suppl.]
  29. Isotalo E, Pyykkö I, Juhola M, Aalto H. Predictable and pseudo random saccades in patients with acoustic neuroma. Acta Oto-laryngol (Stockholm). 1995;520:22–24 (suppl.)
  30. Ron S, Berthoz A. Coupled and dissociated modes of eye–head coordination in humans to flashed visual targets. In:  Schmid R,  Zambarbieri D editor. Oculomotor control and cognitive processes. Amsterdam: Elsevier; 1991;p. 197–211
  31. Ron S, Robinson DA. Eye movements evoked by cerebellar stimulation in the alert monkey. J. Neurophysiol. 1973;36:1004–1022
  32. Kammer T. Phosphenes and transient scotomas induced by magnetic stimulation of the occipital lobe: their topographic relationship. Neuropsychologia. 1999 (Feb.);37(2):191–198
  33. Gothe J, Brandt SA, Irlbacher K, Roricht S, Sabel BA, Meyer BU. Changes in visual cortex excitability in blind subjects as demonstrated by transcranial magnetic stimulation. Brain. 2002 (Mar.);125(Pt. 3):479–490
  34. Kastner S, Demmer I, Ziemenn U. Transient visual field defects induced by transient magnetic stimulation over human occipital pole. Exp. Brain Res. 1998;118:19–26
  35. Suzuki DA, Keller EL. The role of the posterior vermis of monkey cerebellum in smooth pursuit eye movement control. I. Eye and head movement-related activity. J. Neurophysiol. 1988;59:1–18
  36. Suzuki DA, Keller EL. The role of the posterior vermis of monkey cerebellum in smooth pursuit eye movement control. II. Target velocity-related Purkinje cell activity. J. Neurophysiol. 1988;59:19–40
  37. Keller EL, Slakey DP, Crandall WF. Microstimulation of the primate cerebellar vermis during saccadic eye-movements. Brain Res. 1983;288:131–143
  38. Büttner U, Fuchs AF, Markert-Schwab G, Buckmaster P. Fastigial nucleus activity in the alert monkey during slow eye and head movements. J. Neurophysiol. 1991;65:1360–1371
  39. Waitzman DM, Ma TP, Optican LM, Wurtz RH. Superior colliculus neurons mediate the dynamic characteristics of saccades. J. Neurophysiol. 1991;66:1716–1737
  40. Zangemeister WH, Canavan AG, Hoemberg V. Frontal and parietal transcranial magnetic stimulation (TMS) disturbs programming of saccadic eye movements. J. Neurol. Sci. 1995;133:42–52
  41. Takagi M, Zee DS, Tamargo RJ. Effects of lesions of the oculomotor vermis on the eye movements in primate: saccades. J. Neurophysiol. 1998;80:1911–1931
  42. Freeman JA. Responses of cat cerebellar Purkinje cells to convergent inputs from cerebral cortex and peripheral sensory systems. J. Neurophysiol. 1970;33(6):697–712
  43. Fuller JH. Head movement propensity. Exp. Brain Res. 1992;92:152–164
  44. Goldring JE, Dorris MC, Corneil BD, Ballantyne PA, Munoz DP. Combined eye–head gaze shifts to visual and auditory targets in humans. Exp. Brain Res. 1996;111:68–78
  45. Smeets JB, Hayhoe MM, Ballard DH. Goal directed arm movements change eye–head coordination. Exp. Brain Res. 1996;109:434–440
  46. Goossens HH, Van Opstal AJ. Human eye–head coordination in two dimensions under different sensorimotor conditions. Exp. Brain Res. 1997;114:542–560
  47. Robinson FR, Phillips JO, Fuchs AF. Coordination of gaze shifts in primates: brainstem inputs to neck and extraocular motoneuron pools. J. Comp. Neurol. 1994 (Aug. 1);346(1):43–62
  48. Meyer BU, Roricht S, Machetanz J. Reduction of corticospinal excitability by magnetic stimulation over the cerebellum in patients with large defects of one cerebellar hemisphere. Electroencephalogr. Clin. Neurophysiol. 1994 (Oct.);93(5):372–379

PII: S0022-510X(03)00145-X

doi: 10.1016/S0022-510X(03)00145-X

Journal of the Neurological Sciences
Volume 213, Issue 1 , Pages 35-45 , 15 September 2003