Journal of the Neurological Sciences
Volume 213, Issue 1 , Pages 1-6 , 15 September 2003

Progressive increase in incidence and prevalence of multiple sclerosis in Newcastle, Australia: a 35-year study

  • M.H Barnett

      Affiliations

    • Institute of Clinical Neurosciences, Royal Prince Alfred Hospital, Sydney, NSW 2006, Australia
    • Department of Medicine, University of Sydney, Sydney, NSW 2006, Australia
    • ,
  • D.B Williams

      Affiliations

    • Department of Neurology, John Hunter Hospital, Newcastle, NSW, Australia
    • ,
  • S Day

      Affiliations

    • Institute of Clinical Neurosciences, Royal Prince Alfred Hospital, Sydney, NSW 2006, Australia
    • Department of Medicine, University of Sydney, Sydney, NSW 2006, Australia
    • ,
  • P Macaskill

      Affiliations

    • Department of Public Health, University of Sydney, Sydney, NSW, Australia
    • ,
  • J.G McLeod

      Affiliations

    • Corresponding Author InformationCorresponding author. Department of Medicine, University of Sydney, Sydney, NSW 2006, Australia. Tel.: +61-2-9351-3385; fax: +61-2-9351-4018.
    • Institute of Clinical Neurosciences, Royal Prince Alfred Hospital, Sydney, NSW 2006, Australia
    • Department of Medicine, University of Sydney, Sydney, NSW 2006, Australia

Received 26 November 2002 ,Revised 25 March 2003 ,Accepted 4 April 2003.

References 

  1. Hammond SR, McLeod JG, Millingen KS, Stewart-Wynne EG, English D, Holland JT, et al.  The epidemiology of multiple sclerosis in three Australian cities: Perth, Newcastle and Hobart. Brain. 1988;111(Pt 1):1–25
  2. Hammond SR, English D, de Wytt C, Maxwell IC, Millingen KS, Stewart-Wynne EG, et al.  The clinical profile of MS in Australia: a comparison between medium- and high-frequency prevalence zones. Neurology. 1988;38:980–986
  3. PRISMS (Prevention of Relapses and Disability by Interferon beta-1a Subcutaneously in Multiple Sclerosis) Study Group . PRISMS. Randomised double-blind placebo-controlled study of interferon beta-1a in relapsing/remitting multiple sclerosis. Lancet. 1998;352:1498–1504
  4. Li DK, Zhao GJ, Paty DW. Randomized controlled trial of interferon-beta-1a in secondary progressive MS: MRI results. Neurology. 2001;56:1505–1513
  5. Rose AS, Ellison GW, Myers LW, Tourtellotte WW. Criteria for the clinical diagnosis of multiple sclerosis. Neurology. 1976;26:20–22
  6. Armitage P, Berry G. Statistical methods in medical research. Oxford: Blackwell; 1994;
  7. Dobson AJ, Kuulasmaa K, Eberle E, Scherer Y. Confidence intervals for weighted sums of Poisson parameters. Stat. Med. 1991;10:457–462
  8. Allison RD, Millar JHD. Prevalence and familial incidence of disseminated sclerosis. (A report to the Northern Ireland Hospitals Authority on the results of a three-year survey). Ulster Med. J. 1954;23:5–27
  9. Simmons RD, Hall CA, Gleeson P, Everard G, Casse RF, O'Brien ED. Prevalence survey of multiple sclerosis in the Australian capital territory. Intern. Med. J. 2001;31:161–167
  10. Compston DA. Methods of genetic epidemiology in multiple sclerosis. In:  Compston DA editors. McAlpine's multiple sclerosis. London: Churchill Livingstone; 1998;p. 45–61
  11. Forbes RB, Wilson SV, Swingler RJ. The prevalence of multiple sclerosis in Tayside, Scotland: do latitudinal gradients really exist?. J. Neurol. 1999;246:1033–1040
  12. Granieri E, Casetta I, Govoni V, Tola MR, Marchi D, Murgia SB, et al.  The increasing incidence and prevalence of MS in a Sardinian province. Neurology. 2000;55:842–848
  13. Grimaldi LM, Salemi G, Grimaldi G, Rizzo A, Marziolo R, Lo PC, et al.  High incidence and increasing prevalence of MS in Enna (Sicily), southern Italy. Neurology. 2001;57:1891–1893
  14. Gronlie SA, Myrvoll E, Hansen G, Gronning M, Mellgren SI. Multiple sclerosis in North Norway, and first appearance in an indigenous population. J. Neurol. 2000;247:129–1233
  15. McDonnell GV, Hawkins SA. An epidemiologic study of multiple sclerosis in Northern Ireland. Neurology. 1998;50:423–428
  16. Pugliatti M, Sotgiu S, Solinas G, Castiglia P, Pirastru MI, Murgia B, et al.  Multiple sclerosis epidemiology in Sardinia: evidence for a true increasing risk. Acta Neurol. Scand. 2001;103:20–26
  17. Sumelahti ML, Tienari PJ, Wikstrom J, Palo J, Hakama M. Increasing prevalence of multiple sclerosis in Finland. Acta Neurol. Scand. 2001;103:153–158
  18. Wynn DR, Rodriguez M, O'Fallon WM, Kurland LT. A reappraisal of the epidemiology of multiple sclerosis in Olmsted County, Minnesota. Neurology. 1990;40:780–786
  19. Rice-Oxley M, Williams ES, Rees JE. A prevalence survey of multiple sclerosis in Sussex. J. Neurol. Neurosurg. Psychiatry. 1995;58:27–30
  20. Noonan CW, Kathman SJ, White MC. Prevalence estimates for MS in the United States and evidence of an increasing trend for women. Neurology. 2002;58:136–138
  21. Jacobson DL, Gange SJ, Rose NR, Graham NM. Epidemiology and estimated population burden of selected autoimmune diseases in the United States. Clin. Immunol. Immunopathol. 1997;84:223–243
  22. Onkamo P, Vaananen S, Karvonen M, Tuomilehto J. Worldwide increase in incidence of Type I diabetes—the analysis of the data on published incidence trends. Diabetologia. 1999;42:1395–1403

PII: S0022-510X(03)00122-9

doi: 10.1016/S0022-510X(03)00122-9

Journal of the Neurological Sciences
Volume 213, Issue 1 , Pages 1-6 , 15 September 2003

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