Journal of the Neurological Sciences
Volume 205, Issue 1 , Pages 47-50 , 15 December 2002

An assessment of the association between IL-2 gene polymorphisms and Japanese patients with multiple sclerosis

  • Seiji Kikuchi

      Affiliations

    • Department of Neurology, Hokkaido University Graduate School of Medicine, Kita-15 Nishi-7, Kita-ku, 060-8638 Sapporo, Japan
    • ,
  • Masaaki Niino

      Affiliations

    • Corresponding Author InformationCorresponding author. Tel.: +81-11-700-5375; fax: +81-11-700-5356.
    • Department of Neurology, Hokkaido University Graduate School of Medicine, Kita-15 Nishi-7, Kita-ku, 060-8638 Sapporo, Japan
    • ,
  • Toshiyuki Fukazawa

      Affiliations

    • Hokuyukai Neurology Hospital, Sapporo, Japan
    • ,
  • Ichiro Yabe

      Affiliations

    • Department of Neurology, Hokkaido University Graduate School of Medicine, Kita-15 Nishi-7, Kita-ku, 060-8638 Sapporo, Japan
    • ,
  • Kunio Tashiro

      Affiliations

    • Department of Neurology, Hokkaido University Graduate School of Medicine, Kita-15 Nishi-7, Kita-ku, 060-8638 Sapporo, Japan

Received 18 March 2002 ,Revised 30 July 2002 ,Accepted 5 August 2002.

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  12. Niino M, Kikuchi S, Fukazawa T, Yabe I, Sasaki H, Tashiro K. Genetic polymorphisms of IL-1beta and IL-1 receptor antagonist in association with multiple sclerosis in Japanese patients. J. Neuroimmunol. 2001;118:295–299
  13. McDonald WI, Compston A, Edan G, et al.  Recommended diagnostic criteria for multiple sclerosis: guidelines from the International Panel on the diagnosis of multiple sclerosis. Ann. Neurol. 2001;50:121–127
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  16. Feakes R, Sawcer S, Smillie B, Chataway J, Broadley S, Compston A. No evidence for the involvement of interleukin 2 or the immunoglobulin heavy chain gene cluster in determining genetic susceptibility to multiple sclerosis. J. Neurol. Neurosurg. Psychiatry. 2000;68:679

PII: S0022-510X(02)00307-6

Journal of the Neurological Sciences
Volume 205, Issue 1 , Pages 47-50 , 15 December 2002

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