Journal of the Neurological Sciences
Volume 205, Issue 1 , Pages 83-84, 15 December 2002

Acute isolated bulbar palsy with anti-GT1a IgG antibody subsequent to Campylobacter jejuni enteritis

  • Masakazu Onodera

      Affiliations

    • Department of Neurology, Chiba Rosai Hospital, Chiba, Japan
    • ,
  • Masahiro Mori

      Affiliations

    • Corresponding Author InformationCorresponding author. Tel.: +81-43-226-2129; fax: +81-43-226-2160.
    • Department of Neurology, Chiba University School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba, 260-8670 Japan
    • ,
  • Michiaki Koga

      Affiliations

    • Department of Neurology, Dokkyo University School of Medicine, Tochigi, Japan
    • ,
  • Ikuo Kamitsukasa

      Affiliations

    • Department of Neurology, Chiba Rosai Hospital, Chiba, Japan
    • ,
  • Toshio Fukutake

      Affiliations

    • Department of Neurology, Chiba University School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba, 260-8670 Japan
    • ,
  • Takamichi Hattori

      Affiliations

    • Department of Neurology, Chiba University School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba, 260-8670 Japan
    • ,
  • Nobuhiro Yuki

      Affiliations

    • Department of Neurology, Dokkyo University School of Medicine, Tochigi, Japan
    • ,
  • Satoshi Kuwabara

      Affiliations

    • Department of Neurology, Chiba University School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba, 260-8670 Japan

Received 15 May 2002; accepted 15 July 2002.

Abstract 

We describe a patient with acute isolated bulbar palsy following enteritis. A 29-year-old man developed dysphagia and nasal voice without limb weakness, ataxia, or areflexia. High titres of serum anti-GT1a and anti-Campylobacter jejuni IgG antibodies were detected. He was treated with plasmapheresis, resulting in rapid clinical improvement. This case suggests that an acute isolated bulbar palsy may be caused by a pathology relating to Guillain–Barré syndrome (GBS), in which anti-GT1a IgG antibody may have a role.

Keywords:  Guillain–Barré syndrome, Bulbar palsy, Acute oropharyngeal palsy, Anti-ganglioside antibody, GT1a

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PII: S0022-510X(02)00241-1

Journal of the Neurological Sciences
Volume 205, Issue 1 , Pages 83-84, 15 December 2002

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