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Journal of the Neurological Sciences
Volume 194, Issue 1
, Pages 21-28
, 15 February 2002
GCPII (NAALADase) inhibition prevents long-term diabetic neuropathy in type 1 diabetic BB/Wor rats
References
- . Experimental diabetic neuropathy—an update. Diabetologia. 1999;42:773–788
-
.
In:
Sima AAF editors. Chronic complications in diabetes. Oxidative stress and abnormal lipid metabolism in diabetic complication.
Frontiers in animal diabetes research. vol. 1:Amsterdam: Harwood Acad. Publ; 2000;p. 97–130
- . Slowing of motor nerve conduction velocity in streptozotocin-induced diabetic rats is preceded by impaired vasodilatation in arterioles that overlie the sciatic nerve. Int. J. Exp. Diabetes Res. 2000;1:131–143
- . Diabetic neuropathy: evidence for apoptosis and associated mitochondrial dysfunction. Diabetes. 2000;49:1932–1938
- . Excitatory amino acid synaptic mechanisms and neurological function. Trends Pharmacol. Sci. 1986;7:357–363
- . Correlation between amino acid release and neuropathologic outcome in rat brain following middle cerebral artery occlusion. Stroke. 1990;21:1727–1733
-
.
NAALADase inhibition attenuates hyperalgesia in formalin- and acetic acid-induced models of acute pain.
Soc. Neurosci. 1999;25:2230
- . N-acetylated alpha-linked acidic dipeptidase may be involved in axon Schwann cell signaling. J. Neurocytol. 1996;25:499–512
-
.
Inhibition of NAALADase activity promotes myelin formation following mouse sciatic nerve cryo-lesion.
Soc. Neurosci. 1997;23:2302
- Design, synthesis, and biological activity of a potent inhibitor of the neuropeptidase N-acetylated-α-linked acidic dipeptidase. J. Med. Chem. 1996;39:619–622
- Selective inhibition of NAALADase, which converts NAAG to glutamate, reduces ischemic brain injury. Nat. Med. 1999;5:1396–1402
-
.
NAALADase inhibition protects motor neurons against chronic glutamate toxicity.
Soc. Neurosci. 1997;23:2301
-
.
NAALADase inhibition enhances behavioral and morphological recovery following sciatic nerve crush in mice.
Soc. Neurosci. 2000;26:111
- . Diabetic neuropathy—a continuing enigma. Diabetes Metab. Res. Rev. 2000;16:408–433
-
.
A comparison of diabetic polyneuropathy in type II diabetic BBZDR/Wor rats and in type I diabetic BB/Wor rats.
Diabetologia. 2000;43:787–793
- . A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia. Pain. 1988;32:77–88
- . C-peptide prevents and improves chronic type 1 diabetic polyneuropathy in the BB/Wor rat. Diabetologia. 2001;44:889–897
-
.
In:
Garcia JH, Budka H, McKeever PE, Sima AAF editor. Neuropathology, the diagnostic approach. Peripheral neuropathies. Philadelphia: Mosby; 1997;p. 765–809
-
.
Neuropathic and ocular complications in the BB-Wistar rat.
In:
Shafrir E, Renold A editor. Lessons from animal diabetes. London: John Libbey's; 1984;p. 447–453
- . Diabetic autonomic neuropathy. The distribution of structural changes in sympathetic nerves of the BB rat. Am. J. Pathol. 1985;121:138–147
-
.
N-acetylaspartylglutamate selectively activates mGluR3 receptors in transfected cells.
J. Neurochem. 1997;69:1116–1119
- Activation of class II or III metabotropic glutamate receptors protects cultured cortical neurons against excitotoxic degeneration. Eur. J. Neurosci. 1995;7:1906–1913
- . Involvement of increased excitatory amino acids and intracellular Ca2+ concentration in the spinal dorsal horn in an animal model of neuropathic pain. Pain. 1996;68:85–96
- . Modulation of nociceptive transmission by NMDA/glycine site receptor in the ventroposterolateral nucleus of the thalamus. Pain. 2000;84:213–223
- . A pharmacological analysis of mechanical hyperalgesia in streptozotocin diabetic rats. Pain. 1998;76:151–157
- . Spontaneous activity of primary afferent neurons in diabetic BB-Wistar rats. A possible mechanism of chronic diabetic pain. Diabetes. 1985;34:1210–1213
-
.
Voltage-dependent calcium currents are enhanced in dorsal root ganglion neurons from the BB/W diabetic rat.
J. Physiol. (London). 1995;486:313–322
- . Glutamate-induced calcium loads: effects on energy metabolism and neuronal viability. Clin. Exp. Pharmacol. Physiol. 1995;22:303–304
- Brain ischemia and reperfusion: molecular mechanisms of neuronal injury. J. Neurol. Sci. 2000;179:1–33
- . Nerve ischemia in diabetic rats: time-course of development, effect of insulin treatment plus comparison of streptozotocin and BB models. Diabetologia. 1994;37:43–48
- . Brain cell death following ischemia and reperfusion: a proposed biochemical sequence. Crit. Care Med. 1998;16:714–726
- . The effect of ischemia and recirculation on protein synthesis in the rat brain. J. Neurochem. 1977;28:929–934
- . Glucose-induced oxidative stress and programmed cell death in diabetic neuropathy. Eur. J. Pharmacol. 1999;375:217–223
- . Effects of dl-α-lipoic acid on peripheral nerve conduction, blood flow, energy metabolism and oxidative stress in experimental diabetic neuropathy. Diabetes. 2000;49:1006–1015
- . Neurons undergo apoptosis in animal and cell culture models of diabetes. Neurobiol. Dis. 1999;6:347–363
-
.
Inhibition of NAALADase protects neurons against glucose-induced programmed cell death models of diabetic neuropathy.
Soc. Neurosci. 2000;26:605
PII: S0022-510X(01)00670-0
© 2002 Elsevier Science B.V. All rights reserved.
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Journal of the Neurological Sciences
Volume 194, Issue 1
, Pages 21-28
, 15 February 2002
