Journal of the Neurological Sciences
Volume 194, Issue 1 , Pages 11-13 , 15 February 2002

5′-Flanking region polymorphism of the neuronal nitric oxide synthase gene with Parkinson's disease in Taiwan

  • Hsiao-Sui Lo

      Affiliations

    • Department of Neurology, Taiwan Adventist Hospital, Taipei, Taiwan
    • ,
  • Edward L Hogan

      Affiliations

    • Department of Neurology, Medical University of South Carolina, Charleston, SC 29425, USA
    • ,
  • Bing-Wen Soong

      Affiliations

    • Corresponding Author InformationCorresponding author. The Neurological Institute, Taipei Veterans General Hospital, Taipei 11217, Taiwan. Tel.: +886-2-2872-3307; fax: +886-2-2874-8631
    • Department of Neurology, National Yang-Ming University School of Medicine, Taiwan
    • The Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan

Received 4 December 2000 ,Revised 31 October 2001 ,Accepted 31 October 2001.

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  2. Bredt DS, Snyder SH. Nitric oxide mediates glutamate-linked enhancement of cGMP levels in the cerebellum. Proc. Natl. Acad. Sci. U. S. A. 1989;86:9030–9033
  3. Beal MF. Aging, energy and oxidative stress in neurodegenerative disease. Ann. Neurol. 1995;38:357–366
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  5. Perl DP, Olanow CW, Calne DB. Alzheimer's disease and Parkinson's disease: distinct entities or extremes of a spectrum of neurodegeneration?. Ann. Neurol. 1998;44:S19–S31 (suppl.)
  6. Hantraye P, Brouillet E, Ferrante R, et al.  Inhibition of neuronal nitric oxide synthase prevents MPTP-induced parkinsonism in baboons. Nat. Med. 1996;2:1017–1021
  7. Hall AV, Antoniou H, Wang Y, et al.  Structural organization of the human neuronal nitric oxide synthase gene (NOS1). J. Biol. Chem. 1994;269:33082–33090
  8. Blin N, Stafford DW. A general method for isolation of high molecular DNA from eukaryotes. Nucleic Acids Res. 1976;3:2303–2308
  9. Lodish H, Baltimore D, Berk A, Zipursky SL, Matsudaira P, Darnell J. In: Molecular cell biology. 3rd edn.. New York, NY, USA: Scientific American Books; 1995;p. 316; Chapter 9
  10. Eggers-Sedlet B, Kurth MC, Liberman A, Kurth JH. Nitric oxide synthase gene polymorphism associated with Parkinson's disease. Neurology. 1997;48(3, suppl.): A183 P03.098

PII: S0022-510X(01)00666-9

Journal of the Neurological Sciences
Volume 194, Issue 1 , Pages 11-13 , 15 February 2002

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